Evidence map›Paper›PMID 30566234›Full record

ArticleClinical and experimental immunology2019

To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2

S M McLachlan, H A Aliesky, B Rapoport

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Clinical and experimental immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. The NOD Mouse Beyond Autoimmune Diabetes.Frontiers in immunology · 2022
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S M McLachlanThyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, CA, USA.
H A AlieskyThyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, CA, USA.
B RapoportThyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, CA, USA.
Cedars-Sinai Medical Center · US

Funding

THYROTROPIN RECEPTOR IN HEALTH AND DISEASER01DK019289 · NIDDK · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI RAPOPORT, BASIL · 1986 to 2014
$6.1M
MODULATION OF AN ANIMAL MODEL OF HYPERTHYROIDISMR01DK054684 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI MCLACHLAN, SANDRA M · 1999 to 2017
$5.6M
NIDDK NIH HHS R01 DK019289NIDDK NIH HHS R01 DK054684
6 · The paper itself

Abstract

NOD.H2

Indexed as

Sex FactorsAgingAnimalsAntibody FormationAutoantibodiesDiet TherapyDisease Models, AnimalFemaleHumansIodide PeroxidaseIodidesMaleMiceMice, Inbred NODSex CharacteristicsThyroglobulinAutoantibodiesIodide PeroxidaseIodidesThyroglobulinThyrotropinNOD.H2h4 micesexual dimorphismthyroglobulin autoantibodiesthyroid autoimmunitythyroid peroxidase autoantibodiesTSH

Identifiers

PMID30566234
PMCPMC6422661
OpenAlexW2904033337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.