ArticleAndrologia2019
Seminal human papillomavirus originates from the body surface and is not a frequent aetiological factor in azoospermia.
Article in Andrologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Is HPV the Novel Target in Male Idiopathic Infertility? A Systematic Review of the Literature.Frontiers in endocrinology · 2021Pooled it
- Human papillomavirus seminal carriage alters virome diversity and male fertility: a case-control study.Reproductive biology and endocrinology : RB&E · 2025Article
- Human papillomavirus carriage in the semen of men consulting for infertility: prevalence and correlations with sperm characteristics.Asian journal of andrology · 2025Article
- Prevalence of HSV-1/HSV-2 and CMV Infections in Infertile Men and Their Impact on Sperm Parameters: A Cross-Sectional Study in Iran.Health science reports · 2025Article
- Impact of high-risk and low-risk human papillomavirus infections on the male genital tract: effects on semen inflammation and sperm quality.Frontiers in cellular and infection microbiology · 2024Article
- Human Papillomavirus (HPV) Infection and Its Impact on Male Infertility.Life (Basel, Switzerland) · 2022Article
- Genetic instability and anti-HPV immune response as drivers of infertility associated with HPV infection.Infectious agents and cancer · 2021Review
- Prevalence of CBAVD in azoospermic men carrying pathogenic CFTR mutations - Evaluated in a cohort of 639 non-vasectomized azoospermic men.Andrology · 2021Article
- Negative Impact of Elevated DNA Fragmentation and Human Papillomavirus (HPV) Presence in Sperm on the Outcome of Intra-Uterine Insemination (IUI).Journal of clinical medicine · 2021Article
- Seminal human papillomavirus originates from the body surface and is not a frequent aetiological factor in azoospermia.Andrologia · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Human papillomavirus (HPV) DNA has been detected in the testis tissue of 6.5% of 185 men with non-obstructive azoospermia (NOA). Others have suggested that seminal HPV originates from contamination from the genital skin and mucosa. One hundred unselected azoospermic men and 43 normal men undergoing vasectomy were recruited. Testicular biopsies for HPV examination were collected from all the men. Additionally, the normal men undergoing vasectomy delivered a semen sample and had a swab for HPV examination taken from the genital skin before vasectomy. A piece of each Vas deferens obtained during the vasectomy was examined for the presence of HPV. Two of the primarily azoospermic men were shown to have cryptozoospermia. It was not possible to detect HPV in the testis tissue of any of the included 98 azoospermic men or the 43 proven fertile men. In the proven fertile men, HPV DNA was detected in the semen of 15 men (35%), on the genital skin of 28 men (65%), and in the Vas deferens in three cases (7%). In 13 (87%) men with HPV-positive semen samples, HPV DNA was also detected in the skin swabs, and in 11 men (73%), identical HPV genotypes were found in the two locations.
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Registered trials
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