ReviewEquine veterinary journal2019
Serum amyloid A in equine health and disease.
Review in Equine veterinary journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 83 citations in OpenAlex.
- A Universal Bio-Hybrid Nanoparticle Backpack Platform Endows Stem Cells with Microenvironmental Resilience and Sustained Paracrine Signaling.Nano-micro letters · 2026Article
- Evaluation of sequential serum amyloid A measurements for the prediction of sepsis and survival in critically ill neonatal foals.Journal of veterinary internal medicine · 2026Article
- Effects of Exercise Intensity and Duration on Acute-Phase Proteins in Thoroughbred Racehorses.Animals : an open access journal from MDPI · 2026Article
- Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2026Review
- Diagnostic Value of Heparin-Binding Protein (HBP) in Pulmonary Infection After Radical Surgery for Lung Cancer: A Retrospective Study.Health science reports · 2026Article
- Assessing animal welfare impacts of cosmetic manipulations in dromedary camels: insights from oxidative and inflammatory biomarkers.Frontiers in veterinary science · 2026Article
- Reference interval for serum amyloid a in apparently healthy donkeys measured with a donkey-specific ELISA.Frontiers in veterinary science · 2026Article
- Serum amyloid A in the oral microenvironment: implications for inflammation, host-microbe interactions, and disease monitoring.Frontiers in immunology · 2026Review
- Serum Amyloid A Concentrations in Young Japanese Black Cattle: Relationship with Colostrum Intake and Establishing Cut-Off Concentrations.Animals : an open access journal from MDPI · 2025Article
- Enzyme-Linked Immunosorbent Assay (ELISA) Development for Equine Serum Amyloid A (SAA) Determination Using Recombinant Proteins.Methods and protocols · 2025Article
- Differences in bone turnover markers and injury risks between local and international horses: A Victorian Spring Racing Carnival study.Equine veterinary journal · 2025Article
- Comparative analysis of inflammatory biomarkers for the diagnosis of neonatal sepsis: IL-6, IL-8, SAA, CRP, and PCT.Open life sciences · 2025Article
- Blood-based assessment of oxidative stress, inflammation, endocrine and metabolic adaptations in eventing horses accounting for plasma volume shift after exercise.Veterinary medicine and science · 2024Article
- The Welfare of Horses Competing in Three-Barrel Race Events Is Shown to Be Not Inhibited by Short Intervals between Starts.Animals : an open access journal from MDPI · 2024Article
- Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice.Veterinary sciences · 2023Article
- Microbial Profiling of Amniotic Fluid, Umbilical Blood and Placenta of the Foaling Mare.Animals : an open access journal from MDPI · 2023Article
- Review
- Effect of plasma transfusion on serum amyloid A concentration in healthy neonatal foals and foals with failure of transfer of passive immunity.Journal of veterinary internal medicine · 2023Article
- Acute phase proteins levels in horses, after a single carbohydrate overload, associated with cecal alkalinization.Frontiers in veterinary science · 2023Article
- Impact of Lower Airway Inflammation on Fitness Parameters in Standardbred Racehorses.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Serum amyloid A (SAA) is the major acute phase protein in horses. It is produced during the acute phase response (APR), a nonspecific systemic reaction to any type of tissue injury. In the blood of healthy horses, SAA concentration is very low, but it increases dramatically with inflammation. Due to the short half-life of SAA, changes in its concentration in blood closely reflect the onset of inflammation and, therefore, measurement of SAA useful in the diagnosis and monitoring of disease and response to treatment. Increases in SAA concentration have been described in equine digestive, reproductive and respiratory diseases and following surgical procedures. Moreover, SAA has proven useful for detection of some subclinical pathologies that can disturb training and competing in equine athletes. Increasing availability of diagnostic tests for both laboratory and field use adds to SAA's applicability as a reliable indicator of horses' health status. This review article presents the current information on changes in SAA concentrations in the blood of healthy and diseased horses, focussing on clinical application of this biomarker.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.