Evidence map›Paper›PMID 30565316›Full record

ArticleGenetic epidemiology2019

System for Quality-Assured Data Analysis: Flexible, reproducible scientific workflows.

Jerry Fowler, Francis Anthony San Lucas, Paul Scheet

Abstract read
In one paragraph

Article in Genetic epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jerry FowlerDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-6173-9031
Francis Anthony San LucasMolecular Diagnostic, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Paul ScheetDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-5173-7497

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Statistical Methods for Population Genomics and "Next-gen" Sequencing DataR01HG005859 · NHGRI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SCHEET, PAUL A · 2011 to 2015
$1.9M
NCI NIH HHS P30 CA016672NCI NIH HHS P30CA016672NHGRI NIH HHS R01 HG005859NHGRI NIH HHS R01HG005859
6 · The paper itself

Abstract

The reproducibility of scientific processes is one of the paramount problems of bioinformatics, an engineering problem that must be addressed to perform good research. The System for Quality-Assured Data Analysis (SyQADA), described here, seeks to address reproducibility by managing many of the details of procedural bookkeeping in bioinformatics in as simple and transparent a manner as possible. SyQADA has been used by persons with backgrounds ranging from expert programmer to Unix novice, to perform and repeat dozens of diverse bioinformatics workflows on tens of thousands of samples, consuming over 80 CPU-months of computing on over 300,000 individual tasks of scores of projects on laptops, computer servers, and computing clusters. SyQADA is especially well-suited for paired-sample analyses found in cancer tumor-normal studies. SyQADA executable source code, documentation, tutorial examples, and workflows used in our lab is available from http://scheet.org/software.html.

Indexed as

Data AnalysisWorkflowComputational BiologyHumansReproducibility of ResultsSoftwarebioinformaticscancer genomicscomputer softwarereproducibilityworkflow

Identifiers

PMID30565316
PMCPMC6571143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.