Evidence map›Paper›PMID 30565296›Full record

ArticleMagnetic resonance in medicine2019

Non-contrast myocardial infarct scar assessment using a hybrid native T

Chong Duan, Yanjie Zhu, Jihye Jang, Jennifer Rodriguez, Ulf Neisius, Ahmed S Fahmy, Reza Nezafat

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chong DuanDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-9817-5340
Yanjie ZhuDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-9131-689X
Jihye JangDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Jennifer RodriguezDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Ulf NeisiusDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Ahmed S FahmyDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Reza NezafatDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.

Funding

Cardiovascular MRI Characterization of the Arrhythmogenic Heart in Nonischemic CardiomyopathyR01HL129185 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2015 to 2024
$6.4M
Myocardial Tissue Characterization with MR Relaxometry in Heart FailureR01HL129157 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2017 to 2020
$3.2M
MRI Characterization of Arrhythmogenic Scar in Ventricular TachycardiaR21HL127650 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANTER, ELAD, NEZAFAT, REZA · 2015 to 2016
$479k
American Heart Association 15EIA22710040NHLBI NIH HHS R01 HL129157NHLBI NIH HHS R01 HL129185NHLBI NIH HHS R21 HL127650NIH HHS R01HL129157NIH HHS R01HL129185
6 · The paper itself

Abstract

purposeTo develop a gadolinium-free cardiac MR technique that simultaneously exploits native T

methodsA novel hybrid T one and magnetization transfer (HYTOM) method was developed based on the modified look-locker inversion recovery (MOLLI) sequence, with a train of MT-prep pulses placed before the balanced SSFP (bSSFP) readout pulses. Numerical simulations, based on Bloch-McConnell equations, were performed to investigate the effects of MT induced by (1) the bSSFP readout pulses, and (2) the MT-prep pulses, on the measured, "apparent," native T

resultsNumerical simulation and in vivo studies in healthy volunteers demonstrated that MT effects, resulting from on-resonance bSSFP excitation pulses and off-resonance MT-prep pulses, reduce the measured T

conclusionThe proposed HYTOM method simultaneously exploits native T

Indexed as

Magnetic Resonance ImagingAdultAgedAnimalsComputer SimulationContrast MediaFemaleGadoliniumHumansImage Interpretation, Computer-AssistedMagneticsMaleMiddle AgedModels, TheoreticalMyocardial InfarctionNormal DistributionContrast MediaGadoliniumBloch-McConnell equationsmagnetization transferMOLLImyocardial infarctionnative T1

Identifiers

PMID30565296
PMCPMC6442732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.