ArticleJournal of general internal medicine2019
Assessing the Effect of Clinical Inertia on Diabetes Outcomes: a Modeling Approach.
Article in Journal of general internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and Co-prevalence of Comorbidities among Patients with Type 2 Diabetes Mellitus in the MENA Region: A Systematic Review.Current diabetes reviews · 2024Pooled it
- Limited Impact of High Bleeding Risk Calculation and Peri-Procedural Discussion on Dual-Antiplatelet Therapy Duration and Clinical Outcomes After Percutaneous Coronary Intervention.Circulation reports · 2026Article
- Initial conceptual development of a pilot questionnaire for patient-perceived clinical inertia in chronic disease management: an exploratory study with a predominantly Peruvian sample.Frontiers in health services · 2026Article
- Frailty-Informed Deprescribing of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: A Pragmatic Clinical Framework.Clinical interventions in aging · 2026Article
- Forecasting cardiovascular disease risk and burden in China from 2020 to 2030: a simulation study based on a nationwide cohort.Heart (British Cardiac Society) · 2025Observational
- Mandatory monthly outpatient visits could improve therapeutic inertia in patients with poorly controlled type 2 diabetes.Journal of diabetes investigation · 2024Article
- Capsule Commentary on Correa et al., Assessing the Effect of Clinical Inertia on Diabetes Outcomes: a Modeling Approach.Journal of general internal medicine · 2019Article
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4 authors.
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Abstract
backgroundThere are an increasing number of newer and better therapeutic options in the management of diabetes. However, a large proportion of diabetes patients still experience delays in intensification of treatment to achieve appropriate blood glucose targets-a phenomenon called clinical inertia. Despite the high prevalence of clinical inertia, previous research has not examined its long-term effects on diabetes-related health outcomes and mortality.
objectiveWe sought to examine the impact of clinical inertia on the incidence of diabetes-related complications and death. We also examined how the impact of clinical inertia would vary by the length of treatment delay and population characteristics.
designWe developed an agent-based model of diabetes and its complications. The model was parameterized and validated by data from health surveys, cohort studies, and trials. SUBJECTS: We studied a simulated cohort of patients with diabetes in San Antonio, TX. MAIN MEASURES: We examined 25-year incidences of diabetes-related complications, including retinopathy, neuropathy, nephropathy, and cardiovascular disease. KEY
resultsOne-year clinical inertia could increase the cumulative incidences of retinopathy, neuropathy, and nephropathy by 7%, 8%, and 18%, respectively. The effects of clinical inertia could be worse for populations who have a longer treatment delay, are aged 65 years or older, or are non-Hispanic whites.
conclusionClinical inertia could result in a substantial increase in the incidence of diabetes-related complications and mortality. A validated agent-based model can be used to study the long-term effect of clinical inertia and, thus, inform clinicians and policymakers to design effective interventions.
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