SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
Health-related quality of life among adults living with diabetic foot ulcers: a meta-analysis.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Less Is More? Physical Inactivity and Increased Risk of Diabetes-Related Foot Ulceration-A Systematic Review.Diabetes/metabolism research and reviews · 2026Pooled it
- Clinical guidelines on physical activity and exercise therapy for Chinese adults with type 2 diabetes: A clinical practice guideline from the Chinese Society of Endocrinology.Journal of sport and health science · 2026Guideline
- Clinical Evidence of Traditional Medicines in Modulating the Immune Response and Diabetic Wound Healing.Current topics in medicinal chemistry · 2026Pooled it
- Diabetic Foot Ulcer Classification Models Using Artificial Intelligence and Machine Learning Techniques: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Diabetes Foot Ulcer Prevention: A Review of Footwear Width Assessment for At-Risk Feet.Journal of foot and ankle research · 2025Pooled it
- Incidence and risk factors for amputation in Chinese patients with diabetic foot ulcers: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- The financial burden of diabetes-related foot disease in Australia: a systematic review.Journal of foot and ankle research · 2023Pooled it
- Health-related quality of life and associated factors in people with diabetes at high risk of foot ulceration.Journal of foot and ankle research · 2022Trial
- The Effect of Structured Exercise Compared with Education on Neuropathic Signs and Symptoms in People at Risk of Neuropathic Diabetic Foot Ulcers: A Randomized Clinical Trial.Medicina (Kaunas, Lithuania) · 2021Trial
- Effect of a Novel Macrophage-Regulating Drug on Wound Healing in Patients With Diabetic Foot Ulcers: A Randomized Clinical Trial.JAMA network open · 2021Trial
- Effect of a telemedicine intervention for diabetes-related foot ulcers on health, well-being and quality of life: secondary outcomes from a cluster randomized controlled trial (DiaFOTo).BMC endocrine disorders · 2020Trial
- Plantar Foot Microvascular Reactivity and Oxygenation in Type 2 Diabetes and Peripheral Artery Disease: An Exploratory Study.Microcirculation (New York, N.Y. : 1994) · 2026Article
- Psychological and emotional aspects in people with diabetic foot disease: a systematic scoping review.BMC psychology · 2026Article
- Stress and Health-Related Quality of Life in Adults With Type 1 Diabetes: The Mediating Role of Perceived Support and Treatment Adherence.Journal of clinical nursing · 2026Observational
- Validity, Reliability and Responsiveness of Wound-QoL-14 Quality of Life Questionnaire in Patients With Diabetes Related Foot Ulcers.International wound journal · 2026Article
- Preoperative neutrophil-to-lymphocyte ratio is associated with amputation level progression in patients with diabetic foot.Frontiers in surgery · 2026Article
- Patient-Reported Outcomes and Wound-Related Quality of Life in Adults with Diabetic Foot Ulcers Treated with Silicone Superabsorbent Polymer Dressings: Exploratory Results from a Prospective Multicenter Nonrandomized Cohort Study.Medical devices (Auckland, N.Z.) · 2026Article
- Pain and Polypharmacy Diminish with Local Treatment of Mesenchymal Stem Cells Following Systemic Modulation of Inflammation: A Case Regarding Diabetic Foot Ulcers.Current issues in molecular biology · 2025Article
- Psychological determinants of health-related quality of life in primary care patients with diabetic foot ulcers: aBJGP open · 2025Article
- Evaluation of Machine Learning Model Performance in Diabetic Foot Ulcer: Retrospective Cohort Study.JMIR medical informatics · 2025Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo undertake a systematic review of the literature to investigate the HRQOL among adults living with DFUs.
methodsA systematic search of the medical and nursing/health content databases including MEDLINE, CINAHL, and PsycINFO was conducted up to November 2018. The methodological quality of each study was assessed independently by all authors using the Joanna Briggs Institute checklist. Data analysis was conducted using the Comprehensive Meta-analysis software. All analyses were performed using random-effects models and heterogeneity was quantified.
resultsA total of 12 studies were included in the review. Overall, the HRQOL of participants in the studies was poor on four of eight subscales in the SF-36: physical functioning (mean = 42.75, SE 1.5); role physical (mean = 20.61, SE 3.4); general health (mean = 39.52, SE 1.7); and vitality (mean = 45.73, SE 2.8). In addition, presence of pain, high levels of C-reactive protein (> 10 mg/L), ulcer size > 5 cm
conclusionsThis review has provided evidence indicating that people with DFUs have a significantly lower HRQOL. Evidence-based interventions to improve the HRQOL in this group of people is needed.
Indexed as
Identifiers
30565072What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.