Evidence map›Paper›PMID 30565069›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019

The Influence of Age on Complications and Overall Survival After Ivor Lewis Totally Minimally Invasive Esophagectomy.

Nikolaj S Baranov, Frans van Workum, Jolijn van der Maas, Ewout Kouwenhoven, Marc van Det, Frits J H van den Wildenberg, Fatih Polat, Grard A P Nieuwenhuijzen, Misha D P Luyer, Camiel Rosman

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In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Outcomes of curative esophageal cancer surgery in elderly: A meta-analysis.World journal of gastrointestinal oncology · 2021
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nikolaj S BaranovDepartment of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands. nikolaj.baranov@radboudumc.nl.ORCID 0000-0002-8646-2737
Frans van WorkumDepartment of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Jolijn van der MaasDepartment of Surgery, ZGT Hospital, Almelo, The Netherlands.
Ewout KouwenhovenDepartment of Surgery, ZGT Hospital, Almelo, The Netherlands.
Marc van DetDepartment of Surgery, ZGT Hospital, Almelo, The Netherlands.
Frits J H van den WildenbergDepartment of Surgery, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Fatih PolatDepartment of Surgery, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Grard A P NieuwenhuijzenDepartment of Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Misha D P LuyerDepartment of Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Camiel RosmanDepartment of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLZiekenhuis Groep Twente · NLCanisius-Wilhelmina Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of elderly patients suffering from esophageal cancer is increasing, due to an increasing incidence of esophageal cancer and increasing life expectancy. However, the effect of age on morbidity, mortality, and survival after Ivor Lewis total minimally invasive esophagectomy (TMIE) is not well known.

methodsA prospectively documented database from December 2010 to June 2017 was analyzed, including all patients who underwent Ivor Lewis TMIE for esophageal cancer in three Dutch high-volume esophageal cancer centers. Patients younger than 75 years (younger group) were compared to patients aged 75 years or older (elderly group). Baseline patient characteristics and perioperative data were included. Surgical complications were graded using the Clavien-Dindo scale. The primary outcome was postoperative complications Clavien-Dindo ≥ 3. Secondary outcome parameters were postoperative complications, in-hospital mortality, 30- and 90-day mortality and survival.

resultsFour hundred and forty-six patients were included, 357 in the younger and 89 in the elderly group. No significant differences were recorded regarding baseline patient characteristics. There was no significant difference in complications graded Clavien-Dindo ≥ 3 and overall complications, short-term mortality, and survival. Delirium occurred in 27.0% in the elderly and 11.8% in the younger group (p < 0.001). After correction for baseline comorbidity this difference remained significant (p = 0.001). Median hospital length of stay was 13 days in the elderly and 11 days in the younger group (p = 0.010).

conclusionsIvor Lewis TMIE can be safely performed in selected elderly patients without increasing postoperative morbidity and mortality.

Indexed as

AgedAge FactorsEsophageal NeoplasmsEsophagectomyFemaleHospital MortalityHumansLength of StayMaleMiddle AgedMinimally Invasive Surgical ProceduresPostoperative ComplicationsRetrospective StudiesSurvival RateAgedEsophageal neoplasmsEsophagectomyMortalityPostoperative complications

Identifiers

PMID30565069
PMCPMC6591183
OpenAlexW2904354367

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.