Evidence map›Paper›PMID 30565055›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2019

Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease.

Daniel J Cox, Kun Fang, Anthony L McCall, Mark R Conaway, Tom A Banton, Matthew A Moncrief, Anne M Diamond, Ann G Taylor

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02432391 (Self-Monitoring of Blood Glucose), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02432391 nacompletednot on this map

Self-Monitoring of Blood Glucose (SMBG) as an Educational Tool and a Negative Feedback Loop to Reinforce Blood Glucose Lowering and Discourage Blood Glucose Elevating Self-Management Behaviors in Adults With T2DM

TypeinterventionalSponsorUniversity of VirginiaRan2013 to 2015Enrolled47ConditionsDiabetes Mellitus, Type 2ArmsGEM
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. UPLC-ESI-QTOF-MS Profiling of Phenolic Compounds fromMolecules (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Daniel J CoxDepartment of Psychiatry and Neurobehavioral Sciences, Center for Behavioral Medicine Research, University of Virginia School of Medicine, PO Box 800223, Charlottesville, VA, 22908, USA. djc4f@virginia.edu.ORCID http://orcid.org/0000-0002-0910-5306
Kun FangDepartment of Internal Medicine, Hospital of Xi'an Jiaotong University, Xi'an, 710049, Shaan'xi, China.
Anthony L McCallDepartment of Endocrinology and Metabolism, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
Mark R ConawayDepartment of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
Tom A BantonDepartment of Psychiatry and Neurobehavioral Sciences, Center for Behavioral Medicine Research, University of Virginia School of Medicine, PO Box 800223, Charlottesville, VA, 22908, USA.
Matthew A MoncriefDepartment of Psychiatry and Neurobehavioral Sciences, Center for Behavioral Medicine Research, University of Virginia School of Medicine, PO Box 800223, Charlottesville, VA, 22908, USA.
Anne M DiamondDepartment of Psychiatry and Neurobehavioral Sciences, Center for Behavioral Medicine Research, University of Virginia School of Medicine, PO Box 800223, Charlottesville, VA, 22908, USA.
Ann G TaylorDepartment of Acute and Specialty Care, University of Virginia School of Nursing, Charlottesville, VA, 22908, USA.
University of Virginia · USXi'an Jiaotong University · CN

Funding

Treating Type 2 Diabetes by Reducing Postprandial Glucose Elevations: A Paradigm Shift in Lifestyle ModificationR01DK108957 · NIDDK · UNIVERSITY OF VIRGINIA · PI COX, DANIEL JOSEPH · 2016 to 2019
$2.7M
LifeScan 126392National Institute of Diabetes and Digestive and Kidney Diseases DK108957NIDDK NIH HHS R01 DK108957
6 · The paper itself

Abstract

introductionEfforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke.

methodsData from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm.

resultsCompared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke.

conclusionThese secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research.

trial registrationClinicalTrials.gov ID: NCT02432391.

Indexed as

Behavioral medicineCoronary diseasePostprandial hyperglycemiaType 2 diabetes mellitus

Identifiers

PMID30565055
PMCPMC6349282
OpenAlexW2905387082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.