Evidence map›Paper›PMID 30564953›Full record

ArticleMikrochimica acta2018

A fluorometric aptasensor for bisphenol a based on the inner filter effect of gold nanoparticles on the fluorescence of nitrogen-doped carbon dots.

Li Wang, Hai-Xia Cao, Chang-Gang Pan, Yu-Sheng He, Hong-Fei Liu, Li-Hong Zhou, Cai-Qi Li, Guo-Xi Liang

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Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li WangSchool of Pharmacy, Jiangsu University, Zhenjiang, 212013, China. wangjill@126.com.
Hai-Xia CaoSchool of Pharmacy, Jiangsu University, Zhenjiang, 212013, China.
Chang-Gang PanSchool of the Environment, Jiangsu University, Zhenjiang, 212013, China.
Yu-Sheng HeSchool of the Environment, Jiangsu University, Zhenjiang, 212013, China.
Hong-Fei LiuSchool of Pharmacy, Jiangsu University, Zhenjiang, 212013, China.
Li-Hong ZhouSchool of Pharmacy, Jiangsu University, Zhenjiang, 212013, China.
Cai-Qi LiSchool of the Environment, Jiangsu University, Zhenjiang, 212013, China.
Guo-Xi LiangSchool of the Environment, Jiangsu University, Zhenjiang, 212013, China. gxliang@ujs.edu.cn.

Funding

Advanced Talents Science Foundation of Jiangsu University 10JDG038Advanced Talents Science Foundation of Jiangsu University 10JDG052National Natural Science Foundation of China 21707053Natural Science Foundation of Jiangsu Province BK20140577
6 · The paper itself

Abstract

An aptamer-based fluorometric assay is described for the determination of bisphenol A (BPA). The aptamer against BPA is first attached to the surface of the red AuNPs, and this prevents the AuNPs from salt-induced formation of a blue-colored aggregate. Hence, the blue fluorescence of added nitrogen-doped carbon dots (NCDots) is quenched via an inner filter effect (IFE) caused by the red AuNPs. After addition of BPA, the BPA/aptamer complex is formed, and the AuNPs are no longer stabilized agains aggregation. This weakens the IFE and results in the recovery of the fluorescence of the NCDots which is measured best at excitation/emission wavelengths of 300/420 nm. The recovered fluorescence increases linearly in the 10 to 250 nM and 250 to 900 nM BPA concentration ranges, and the detection limit is 3.3 nM. The method was successfully applied to the determination of BPA in spiked environmental tap water samples. Graphical abstract Schematic presentation of a fluorometric aptamer based assay for bisphenol A (BPA). It is based on the inner filter effect of gold nanoparticles (AuNPs) on the fluorescence of nitrogen-doped carbon dots (NCDots).

Indexed as

Aggregated AuNPsBPA/aptamer complexesEnvironmental-friendlyFluorescence quenchedFluorescence recoveryLow detection limitQuick responseSalt-induced aggregationTap waterWide linear range

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.