Evidence map›Paper›PMID 30564841›Full record

ReviewCellular and molecular life sciences : CMLS2019

Meiotic spindle assembly checkpoint and aneuploidy in males versus females.

Simon Lane, Liisa Kauppi

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.Advances in experimental medicine and biology · 2026
    Review
  7. Review
  8. Article
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  10. Review
  11. Article
  12. Article
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  15. Article
  16. Article
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  18. Bypassing Mendel's First Law: Transmission Ratio Distortion in Mammals.International journal of molecular sciences · 2023
    Review
  19. Article
  20. Prdm9 deficiency of rat oocytes causes synapsis among non-homologous chromosomes and aneuploidy.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Simon LaneDepartment of Chemistry and the Institute for Life Sciences, University of Southampton, Building 85, Highfield Campus, Southampton, SO171BJ, UK.
Liisa KauppiFaculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00014, Helsinki, Finland. liisa.kauppi@helsinki.fi.ORCID http://orcid.org/0000-0002-6759-8997

Funding

Academy of Finland 256996Academy of Finland 292789Academy of Finland 306026Academy of Finland 314394Engineering and Physical Sciences Research Council EP/R041814/1
6 · The paper itself

Abstract

The production of gametes (sperm and eggs in mammals) involves two sequential cell divisions, meiosis I and meiosis II. In meiosis I, homologous chromosomes segregate to different daughter cells, and meiosis II resembles mitotic divisions in that sister chromatids separate. While in principle the process is identical in males and females, the time frame and susceptibility to chromosomal defects, including achiasmy and cohesion weakening, and the response to mis-segregating chromosomes are not. In this review, we compare and contrast meiotic spindle assembly checkpoint function and aneuploidy in the two sexes.

Indexed as

AneuploidyAnimalsChromatidsChromosome SegregationFemaleHumansMaleMeiosisM Phase Cell Cycle CheckpointsSpindle ApparatusAneuploidyChiasmaChromosome segregationCohesinCrossoverMeiosisOocyteRecombinationSpermatocytes

Identifiers

PMID30564841
PMCPMC6513798

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.