ArticleCommunications biology2018
Multiple animal positioning system shows that socially-reared mice influence the social proximity of isolation-reared cagemates.
Article in Communications biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed.
- Cortical regulation of collective social dynamics during environmental challenge.Nature neuroscience · 2026Article
- Preimplantational ethanol exposure causes disturbances in gene expression and abnormalities in cerebral cortex morphogenesis and behavior.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Huddling substates in mice facilitate dynamic changes in body temperature and are modulated by Shank3b and Trpm8 mutation.Communications biology · 2024Article
- Recovery from social isolation requires dopamine in males, but not the autism-related geneRoyal Society open science · 2024Article
- Huddling substates in mice facilitate dynamic changes in body temperature and are modulated byResearch square · 2024Article
- Neural cell-types and circuits linking thermoregulation and social behavior.Neuroscience and biobehavioral reviews · 2024Review
- Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior.Molecular psychiatry · 2024Article
- Long-term monitoring of huddling behavior in mice using online image processing.Neuropsychopharmacology reports · 2024Article
- Advancements in Passive Wireless Sensors, Materials, Devices, and Applications.Sensors (Basel, Switzerland) · 2023Review
- Long-term behavioral effects of social separation during early life in a social mammal, Octodon degus.Scientific reports · 2023Article
- Differences in long-term effects of standard rodent diets on blood glucose and body weight of offspring.Diabetology international · 2022Article
- Social deficits in BTBR T+ Itpr3tf/J mice vary with ecological validity of the test.Genes, brain, and behavior · 2022Article
- O mouse, where art thou? The Mouse Position Surveillance System (MoPSS)-an RFID-based tracking system.Behavior research methods · 2022Article
- Marker-less tracking system for multiple mice using Mask R-CNN.Frontiers in behavioral neuroscience · 2022Article
- Mouse Model of Weak Depression Exhibiting Suppressed cAMP Signaling in the Amygdala, Lower Lipid Catabolism in Liver, and Correlated Gut Microbiota.Frontiers in behavioral neuroscience · 2022Article
- Childhood social isolation causes anxiety-like behaviors via the damage of blood-brain barrier in amygdala in female mice.Frontiers in cell and developmental biology · 2022Article
- Early life stress exacerbates behavioural and neuronal alterations in adolescent male mice lacking methyl-CpG binding protein 2 (Mecp2).Frontiers in behavioral neuroscience · 2022Article
- Cupid's quiver: Integrating sensory cues in rodent mating systems.Frontiers in neural circuits · 2022Review
- The effects of maternal separation on behaviours under social-housing environments in adult male C57BL/6 mice.Scientific reports · 2021Article
- Effects of Early-Life Stress on the Brain and Behaviors: Implications of Early Maternal Separation in Rodents.International journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Social relationships are a key determinant of social behaviour, and disruption of social behaviour is a major symptom of several psychiatric disorders. However, few studies have analysed social relationships among multiple individuals in a group or how social relationships within a group influence the behaviour of members with impaired socialisation. Here, we developed a video-analysis-based system, the Multiple-Animal Positioning System (MAPS), to automatically and separately analyse the social behaviour of multiple individuals in group housing. Using MAPS, we show that social isolation of male mice during adolescence leads to impaired social proximity in adulthood. The phenotype of these socially isolated mice was partially rescued by cohabitation with group-housed (socially-reared) mice, indicating that both individual behavioural traits and those of cagemates influence social proximity. Furthermore, we demonstrate that low reactive behaviour of other cagemates also influence individual social proximity in male mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.