Evidence map›Paper›PMID 30564728›Full record

ArticleBJGP open2018

Development of an intervention to expedite cancer diagnosis through primary care: a protocol.

Marian Andrei Stanciu, Rebecca-Jane Law, Sadia Nafees, Maggie Hendry, Seow Tien Yeo, Julia Hiscock, Ruth Lewis, Rhiannon T Edwards, Nefyn H Williams, Katherine Brain and 14 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJGP open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 4 countries.

Marian Andrei StanciuResearch Officer, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Rebecca-Jane LawResearch Officer, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Sadia NafeesResearch Project Support Officer, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Maggie HendryResearch Fellow, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Seow Tien YeoResearch Fellow, Centre for Health Economics and Medicines Evaluation (CHEME), Bangor University, Bangor, UK.
Julia HiscockResearch Fellow, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Ruth LewisResearch Fellow in Health Sciences Research, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Rhiannon T EdwardsProfessor of Health Economics, Centre for Health Economics and Medicines Evaluation (CHEME), Bangor University, Bangor, UK.
Nefyn H WilliamsProfessor in Primary Care, Department of Health Services Research, University of Liverpool, Liverpool, UK.
Katherine BrainProfessor, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Paul BrocklehurstProfessor in Health Services Research, North Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, UK.
Andrew Carson-StevensClinical Reader, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Sunil DolwaniSenior Clinical Lecturer, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Jon EmeryProfessor of Primary Care Cancer Research, Department of General Practice and Centre for Cancer Research, University of Melbourne, Melbourne, Australia.
William HamiltonProfessor of Primary Care Diagnostics, Discovery Research Group, University of Exeter, Exeter, UK.
Zoe HoarePrincipal Trial Statistician, North Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, UK.
Georgios LyratzopoulosProfessor of Cancer Epidemiology, Department of Behavioural Science and Health, University College London, London, UK.
Greg RubinProfessor of General Practice and Primary Care, Institute of Health and Society, University of Newcastle, Newcastle, UK.
Stephanie SmitsResearch Associate, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Peter VedstedProfessor, Research Director, Department of Public Health, Research Centre for Cancer Diagnosis, Research Unit for General Practice, Aarhus University, Aarhus, Denmark.
Fiona WalterPrincipal Researcher in Primary Care Cancer Research, Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Clare WilkinsonProfessor of General Practice, North Wales Centre for Primary Care Research, Bangor University, Wrexham, UK.
Richard D NealProfessor of Primary Care Oncology, Academic Unit of Primary Care, Institute of Health Sciences, University of Leeds, Leeds, UK.
WICKED Team on behalf of
Bangor University · GBCardiff University · GBMedicines Evaluation Unit · GBPrimary Health Care · QAAarhus University · DKUniversity College London · GBUniversity of Cambridge · GBUniversity of Exeter · GBUniversity of Leeds · GBUniversity of Liverpool · GBUniversity of Melbourne · AU

Funding

Cancer Research UK 18180
6 · The paper itself

Abstract

backgroundGPs can play an important role in achieving earlier cancer diagnosis to improve patient outcomes, for example through prompt use of the urgent suspected cancer referral pathway. Barriers to early diagnosis include individual practitioner variation in knowledge, attitudes, beliefs, professional expectations, and norms.

aimThis programme of work (Wales Interventions and Cancer Knowledge about Early Diagnosis [WICKED]) will develop a behaviour change intervention to expedite diagnosis through primary care and contribute to improved cancer outcomes. DESIGN &

settingNon-experimental mixed-method study with GPs and primary care practice teams from Wales.

methodFour work packages will inform the development of the behaviour change intervention. Work package 1 will identify relevant evidence-based interventions (systematic review of reviews) and will determine why interventions do or do not work, for whom, and in what circumstances (realist review). Work package 2 will assess cancer knowledge, attitudes, and behaviour of GPs, as well as primary care teams' perspectives on cancer referral and investigation (GP survey, discrete choice experiment [DCE], interviews, and focus groups). Work package 3 will synthesise findings from earlier work packages using the behaviour change wheel as an overarching theoretical framework to guide intervention development. Work package 4 will test the feasibility and acceptability of the intervention, and determine methods for measuring costs and effects of subsequent behaviour change in a randomised feasibility trial.

resultsThe findings will inform the design of a future effectiveness trial, with concurrent economic evaluation, aimed at earlier diagnosis.

conclusionThis comprehensive, evidence-based programme will develop a complex GP behaviour change intervention to expedite the diagnosis of symptomatic cancer, and may be applicable to countries with similar healthcare systems.

Indexed as

discrete choice experimentearly cancer diagnosisgeneral practitionershospital referralprimary carequalitativerealist synthesissurvey

Identifiers

PMID30564728
PMCPMC6189786
OpenAlexW2890887681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.