ReviewBrain plasticity (Amsterdam, Netherlands)2018
Exercise Improves Vascular Function, but does this Translate to the Brain?
Review in Brain plasticity (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Biological Sex and Age on Cerebral Blood Flow and Vessel Function During Exercise: a Pilot Study
Influence of Biological Sex and Age on Cerebral Blood Flow and Vessel Function During Exercise: a Pilot Study
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- The impact of walking training on cognitive function in older adults: a meta-analysis.Frontiers in psychology · 2026Pooled it
- Look into my eyes: What can eye-based measures tell us about the relationship between physical activity and cognitive performance?Journal of sport and health science · 2023Pooled it
- The acute effect of two exercise modalities on neurocognitive responses in postmenopausal women: A randomized controlled trial.Experimental physiology · 2026Trial
- The independent and combined effects of aerobic exercise intensity and dose differentially increase post-exercise cerebral shear stress and blood flow.Experimental physiology · 2024Trial
- The Effects of Exergame Telerehabilitation in Persons With Subjective Cognitive Decline.The Gerontologist · 2024Trial
- Aerobic exercise training and neurocognitive function in cognitively normal older adults: A one-year randomized controlled trial.Journal of internal medicine · 2022Trial
- Higher VOScientific reports · 2021Trial
- Exercise training improves vascular function in patients with Alzheimer's disease.European journal of applied physiology · 2020Trial
- Inflammatory, metabolic, and vascular pathways linking cardiorespiratory fitness to cognition: Results from the IGNITE study.Brain, behavior, & immunity - health · 2026Article
- Associations among dynamic cerebral autoregulation, baroreflex sensitivity, and carotid distensibility in young healthy adults: insight from endurance training.European journal of applied physiology · 2026Article
- Impact of exercise on cognitive efficiency in older adults with subjective memory complaints: a randomized clinical trial.Frontiers in aging neuroscience · 2026Article
- Design of Trials for Cerebral Small Vessel Disease and Vascular Cognitive Impairment.Neurology international · 2025Review
- Fitness and exercise effects on brain age: A randomized clinical trial.Journal of sport and health science · 2025Article
- Group and partnered dance for people living with dementia: an overview of intervention design and measurement considerations.Frontiers in psychology · 2025Article
- Characterizing the cognitive and mental health benefits of exercise and video game playing.PloS one · 2025Article
- Article
- Exercise as a Therapeutic Strategy to Improve Cerebrovascular Function and Cognition in Breast Cancer Survivors: A Scoping Review.Journal of clinical medicine · 2024Article
- The Effect of Physical Exercise on Patients With Mild Cognitive Impairment: A Scoping Review.Cureus · 2024Article
- Greater physical fitness (Acta physiologica (Oxford, England) · 2024Article
- The Impact of Different Exercise Modes in Fitness and Cognitive Indicators: Hybrid versus Tele-Exercise in Patients with Long Post-COVID-19 Syndrome.Brain sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The number of adults with Alzheimer's disease (AD) or related dementia is expected to increase exponentially. Interventions aimed to reduce the risk and progression of AD and dementia are critical to the prevention and treatment of this devastating disease. Aging and cardiovascular disease risk factors are associated with reduced vascular function, which can have important clinical implications, including brain health. The age-associated increase in blood pressure and impairment in vascular function may be attenuated or even reversed through lifestyle behaviors. Greater volumes of habitual exercise and higher cardiorespiratory fitness are associated with beneficial effects on vascular health and cognition. Exercise and cardiorespiratory fitness may be most important during midlife, as physical activity and cardiorespiratory fitness during the middle-aged years are associated with future cognitive function. The extent to which exercise, and more specifically aerobic exercise, influences the cerebral circulation is not well established. In this review, we present our working hypothesis showing how cerebrovascular function may be a mediating factor underlying the association between exercise and cognition, as well as discuss recent studies evaluating the effect of exercise interventions on the cerebral circulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.