ArticlePilot and feasibility studies2018
Cardiac rehabilitation to improve health-related quality of life following trans-catheter aortic valve implantation: a randomised controlled feasibility study: RECOVER-TAVI Pilot, ORCA 4, For the Optimal Restoration of Cardiac Activity Group.
Article in Pilot and feasibility studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02921880 (Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement?), which is not on this map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement?
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Prevalence and course of depression in older people with aortic stenosis undergoing transcatheter aortic valve implantation - a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Comprehensive geriatric assessment, and related interventions, to improve outcomes for older patients undergoing transcatheter aortic valve implantation (TAVI): a systematic review.European geriatric medicine · 2024Pooled it
- Exercise as the Key to Improve Cardiopulmonary Function in Patients with Valvular Heart Disease: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Exercise-based cardiac rehabilitation for adults after heart valve surgery.The Cochrane database of systematic reviews · 2021Pooled it
- Long term efficacy and safety of MICT of cardiopulmonary function in patients after TAVR extended follow up of ENERGY study.Scientific reports · 2025Trial
- Home-Based Rehabilitation After Transcatheter Aortic Valve Replacement (REHAB-TAVR): A Pilot Randomized Controlled Trial.Journal of the American Geriatrics Society · 2025Trial
- Traditional and Virtual Cardiac Rehabilitation: Understanding the Changing Landscape of Cardiac Rehabilitation and the Implications on Patient Outcomes.Reviews in cardiovascular medicine · 2025Review
- Understanding Frailty in Cardiac Rehabilitation: A Scoping Review of Prevalence, Measurement, Sex and Gender Considerations, and Barriers to Completion.Journal of clinical medicine · 2025Review
- Exercise-based real-time telerehabilitation for older patients recently discharged after transcatheter aortic valve implantation: An extended feasibility study.Journal of geriatric cardiology : JGC · 2023Article
- Physical Performance in Black and Hispanic Outpatients With Heart Failure: The SCAN-MP Study.CJC open · 2023Article
- Exercise-Based Real-time Telerehabilitation for Older Adult Patients Recently Discharged After Transcatheter Aortic Valve Implantation: Mixed Methods Feasibility Study.JMIR rehabilitation and assistive technologies · 2022Article
- Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2022Review
- Balloon Aortic Valvuloplasty for Severe Aortic Stenosis as Rescue or Bridge Therapy.Journal of clinical medicine · 2021Article
- Inpatient Cardiac Rehabilitation after Transcatheter Aortic Valve Replacement Is Associated with Improved Clinical Performance and Quality of Life.Journal of clinical medicine · 2021Article
- Are the group-based interventions improving the functional exercise capacity and quality of life of frail subjects with chronic heart failure?Journal of frailty, sarcopenia and falls · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTranscatheter aortic valve implantation (TAVI) is often undertaken in the oldest frailest cohort of patients undergoing cardiac interventions. We plan to investigate the potential benefit of cardiac rehabilitation (CR) in this vulnerable population.
designWe undertook a pilot randomised trial of CR following TAVI to inform the feasibility and design of a future randomised clinical trial (RCT).
participantsWe screened patients undergoing TAVI at a single institution between June 2016 and February 2017.
interventionsParticipants were randomised post-TAVI to standard of care (control group) or standard of care plus exercise-based CR (intervention group). OUTCOMES: We assessed recruitment and attrition rates, uptake of CR, and explored changes in 6-min walk test, Nottingham Activities of Daily Living, Fried and Edmonton Frailty scores and Hospital Anxiety and Depression Score, from baseline (30 days post TAVI) to 3 and 6 months post randomisation. We also undertook a parallel study to assess the use of the Kansas City Cardiomyopathy Questionnaire (KCCQ) in the post-TAVI population.
resultsOf 82 patients screened, 52 met the inclusion criteria and 27 were recruited (3 patients/month). In the intervention group, 10/13 (77%) completed the prescribed course of 6 sessions of CR (mean number of sessions attended 7.5, SD 4.25) over 6 weeks. At 6 months, all participants were retained for follow-up. There was apparent improvement in outcome scores at 3 and 6 months in control and CR groups. There were no recorded adverse events associated with the intervention of CR. The KCCQ was well accepted in 38 post-TAVI patients: mean summary score 72.6 (SD 22.6).
conclusionsWe have demonstrated the feasibility of recruiting post-TAVI patients into a randomised trial of CR. We will use the findings of this pilot trial to design a fully powered multicentre RCT to inform the provision of CR and support guideline development to optimise health-related quality of life outcomes in this vulnerable population. Retrospectively registered 3rd October 2016 clinicaltrials.gov NCT02921880.
trial registrationClinicaltrials.Gov identifier NCT02921880.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.