ArticleJournal of intensive care2018
Trends of loss of peripheral muscle thickness on ultrasonography and its relationship with outcomes among patients with sepsis.
Article in Journal of intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 6 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Diagnostic and application guidelines for malnutrition in adult patients (2025 edition).Asia Pacific journal of clinical nutrition · 2025Guideline
- Acute Sarcopenia: Systematic Review and Meta-Analysis on Its Incidence and Muscle Parameter Shifts During Hospitalisation.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Growth differentiation factor-15 as a biomarker for intensive care unit-acquired weakness: a meta-analysis.Frontiers in medicine · 2025Pooled it
- Impact of Muscle Changes Assessed by Ultrasonography on Muscle Strength and Functioning after ICU Discharge: A Systematic Review with Meta-Analysis.International journal of environmental research and public health · 2024Pooled it
- Expert Consensus on Morphofunctional Assessment in Disease-Related Malnutrition. Grade Review and Delphi Study.Nutrients · 2023Pooled it
- The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Methodological Approaches for Ultrasound Assessment of Peripheral and Abdominal Muscle Thickness in Intensive Care: A Scoping Review and Proposed Reporting Framework.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Ultrasound assessment of muscle atrophy and its association with functional outcomes in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2026Review
- Ultrasound- and circumference-based quadriceps mass is an independent predictor of 28-day mortality in critically ill patients.Frontiers in nutrition · 2026Article
- Different trend of muscle wasting extracted from computed tomography in patients with severe acute pancreatitis.Abdominal radiology (New York) · 2025Article
- Evaluating skeletal muscle wasting and weakness in models of critical illness.Clinical science (London, England : 1979) · 2025Review
- Evaluation of the correlation between pre-anaesthetic P-POSSUM score, ultrasound muscle assessment and frailty index on perioperative outcome - An observational trial.Indian journal of anaesthesia · 2025Article
- Disease entity impacts muscle wasting in the ICU with COVID-19 patients losing muscle nearly twice as fast.Scientific reports · 2025Article
- The extent of Skeletal muscle wasting in prolonged critical illness and its association with survival: insights from a retrospective single-center study.BMC anesthesiology · 2025Article
- Quadriceps muscle thickness as measured by point-of-care ultrasound is associated with hospital length of stay among hospitalised older patients.Age and ageing · 2025Article
- Risk Factors, Diagnostic Challenges, and Emerging Therapeutic Strategies for ICU-Acquired Weakness: A Brief Review.Journal of multidisciplinary healthcare · 2025Review
- Ultrasonographic examination of masticatory muscles in patients with TMJ arthralgia and headache attributed to temporomandibular disorders.Scientific reports · 2024Article
- Muscle Dysfunction and Functional Status in COVID-19 Patients during Illness and after Hospital Discharge.Biomedicines · 2024Article
- Reply to: Association between rectus femoris cross-sectional area and diaphragmatic excursion with weaning of tracheostomized patients in the intensive care unit.Critical care science · 2024Article
- Ultrasonographic Features of Muscular Weakness and Muscle Wasting in Critically Ill Patients.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsData regarding trends of muscle loss on ultrasonography (USG) and its relationship with various outcomes among critically ill patients is limited. This study aimed to describe the trends of loss of muscle thickness of the arm and thigh (assessed using USG) and to determine the relationship between loss of muscle thickness and in-hospital and post-discharge outcomes.
methodsMuscle thickness of 70 patients with sepsis was measured at the level of the mid-arm and mid-thigh using bedside USG on days 1, 3, 5, 7, 10 and 14 and then weekly till discharge or death. Patients were followed up for 90 days after discharge.
resultsThe muscle thickness (mean ± SD) at the level of the mid-arm and mid-thigh on day 1 was 23.13 ± 4.83 mm and 31.21 ± 8.56 mm, respectively. The percentage muscle thickness [median (min, max)] decline at the mid-arm and mid-thigh was 7.61 (- 1.51, 32.05)% and 10.62 (- 1.48, 32.06)%, respectively on day 7 as compared to baseline (
conclusionsCritically ill patients with sepsis exhibit a gradual decline in muscle thickness of both the arm and thigh. Decline in muscle thickness was associated with in-hospital mortality. USG has a potential to identify patients at risk of worse in-hospital and post-discharge outcomes.
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