Evidence map›Paper›PMID 30564340›Full record

ArticleClinical case reports2018

An unusual presentation of a patient with severe hypogammaglobulinemia.

Thijs W Hoffman, Diana A van Kessel, Maarten J D van Tol, Gestur Vidarsson, Els C Jol-van der Zijde, Ger T Rijkers, Heleen van Velzen-Blad

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thijs W HoffmanDepartment of Pulmonology St. Antonius Hospital Nieuwegein The Netherlands.ORCID 0000-0002-0186-0040
Diana A van KesselDepartment of Pulmonology St. Antonius Hospital Nieuwegein The Netherlands.
Maarten J D van TolDepartment of Pediatrics Leiden University Medical Center Leiden The Netherlands.
Gestur VidarssonDepartment of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center University of Amsterdam Amsterdam The Netherlands.
Els C Jol-van der ZijdeDepartment of Pediatrics Leiden University Medical Center Leiden The Netherlands.
Ger T RijkersDepartment of Medical Microbiology and Immunology St. Antonius Hospital Nieuwegein The Netherlands.
Heleen van Velzen-BladDepartment of Medical Microbiology and Immunology St. Antonius Hospital Nieuwegein The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a patient who was diagnosed with severe hypogammaglobulinemia after her newborn child presented with two episodes of meningitis. The patient had no history or symptoms suggestive of immunodeficiency. Thus far, a cause for the immunodeficiency has not been found, even after extensive immunological evaluation.

Indexed as

antibody replacement therapyhypogammaglobulinemiaimmunodeficiencyprimary antibody deficiencyvaccination response

Identifiers

PMID30564340
PMCPMC6293131

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.