Evidence map›Paper›PMID 30564276›Full record

ReviewThe journal of venomous animals and toxins including tropical diseases2018

Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties.

Marco Aurélio Sartim, Danilo Luccas Menaldo, Suely Vilela Sampaio

Open access · goldAbstract readReview
In one paragraph

Review in The journal of venomous animals and toxins including tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Crotoxin Upregulating NLRP-3 Inflammasome and IL-18 and Activating CD4Animals : an open access journal from MDPI · 2026
    Article
  2. Crotoxin fromFrontiers in immunology · 2026
    Article
  3. Snake Venom PLAToxins · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Cytotoxic effects of crotoxin fromThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  8. Fraction ofThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  9. Review
  10. Review
  11. Antibacterial Properties of Crotoxin fromMolecules (Basel, Switzerland) · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Frontiers in immunology · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marco Aurélio SartimDepartamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto-SP, 14040-903 Brazil.
Danilo Luccas MenaldoDepartamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto-SP, 14040-903 Brazil.
Suely Vilela SampaioDepartamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto-SP, 14040-903 Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the past 80 years, Crotoxin has become one of the most investigated isolated toxins from snake venoms, partially due to its major role as the main toxic component in the venom of the South American rattlesnake

Indexed as

Adaptative immunityCrotalus durissus terrificusCrotoxinInflammationInnate immunity

Identifiers

PMID30564276
PMCPMC6296157
OpenAlexW2904783264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.