Evidence map›Paper›PMID 30564240›Full record

ArticleFrontiers in immunology2018

Extensive Alternative Splicing of KIR Transcripts.

Jesse Bruijnesteijn, Marit K H van der Wiel, Nanine de Groot, Nel Otting, Annemiek J M de Vos-Rouweler, Neubury M Lardy, Natasja G de Groot, Ronald E Bontrop

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Emerging roles of KIR2DL4 in cancer immunotherapy.Breast cancer (Tokyo, Japan) · 2025
    Review
  2. Review
  3. Frontiers in immunology · 2025
    Article
  4. Review
  5. TheFrontiers in immunology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Genetic Variants inFrontiers in immunology · 2021
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jesse BruijnesteijnComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Marit K H van der WielComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Nanine de GrootComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Nel OttingComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Annemiek J M de Vos-RouwelerComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Neubury M LardyDepartment of Immunogenetics, Sanquin, Amsterdam, Netherlands.
Natasja G de GrootComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Ronald E BontropComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Biomedical Primate Research Centre · NLSanquin · NLUtrecht University · NL

Funding

NIAID NIH HHS HHSN272201600007C
6 · The paper itself

Abstract

The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules. The complexity of the

Indexed as

Alternative SplicingAnimalsDNA Copy Number VariationsExonsHistocompatibility Antigens Class IHumansMacaca mulattaProtein IsoformsReceptors, KIRHistocompatibility Antigens Class IProtein IsoformsReceptors, KIRalternative splicinghumankiller cell immunoglobin-like receptorKIRNK cellrhesus macaque (Macaca mulatta)

Identifiers

PMID30564240
PMCPMC6288254
OpenAlexW2903196056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.