Evidence map›Paper›PMID 30564213›Full record

ArticleFrontiers in microbiology2018

Concomitant Temperature Stress and Immune Activation may Increase Mortality Despite Efficient Clearance of an Intracellular Bacterial Infection in Atlantic Cod.

Anett K Larsen, Ingebjørg H Nymo, Karen K Sørensen, Marit Seppola, Rolf Rødven, María Pilar Jiménez de Bagüés, Sascha Al Dahouk, Jacques Godfroid

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Thermal and Nutritional Strategies for ManagingAnimals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Anett K LarsenArctic Infection Biology, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, Tromsø, Norway.
Ingebjørg H NymoArctic Infection Biology, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, Tromsø, Norway.
Karen K SørensenDepartment of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway.
Marit SeppolaDepartment of Medical Biology, UiT - The Arctic University of Norway, Tromsø, Norway.
Rolf RødvenDepartment of Research and Development, UiT - The Arctic University of Norway, Tromsø, Norway.
María Pilar Jiménez de BagüésUnidad de Tecnología en Producción y Sanidad Animal, Centro de Investigación y Tecnología Agroalimentaria, Instituto Agroalimentario de Aragón, Universidad de Zaragoza, Zaragoza, Spain.
Sascha Al DahoukGerman Federal Institute for Risk Assessment, Berlin, Germany.
Jacques GodfroidArctic Infection Biology, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, Tromsø, Norway.
UiT The Arctic University of Norway · NOCentro de Investigación y Tecnología Agroalimentaria de Aragón · ESFederal Institute for Risk Assessment · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The environmental temperature has profound effects on biological systems of marine aquatic organisms and plays a critical role in species distribution and abundance. Particularly during the warmer seasons, variations in habitat temperature may introduce episodes of stressful temperatures which the organisms must adapt to and compensate for to maintain physiological homeostasis. The marine environment is changing and predicted raises in water temperatures will affect numerous marine species. Translocation of pathogens follow migration of species and alternations in physical environmental parameters may have influence upon the virulence of pathogens, as well as the hosts immune responses. While pathogenicity of many true pathogens is expected to increase following climate induced temperature stress, the impact from environmental stressors on the occurrence and severity of opportunistic infections is unknown. Here we describe how thermal stress in the cold-water species Atlantic cod influenced the fish immune responses against an opportunistic intracellular bacterium. Following experimental infection with

Indexed as

Brucellaclimate changedisease resistanceGadus morhuaimmunologyopportunistic infectionstresstemperature

Identifiers

PMID30564213
PMCPMC6289035
OpenAlexW2903469669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.