Evidence map›Paper›PMID 30564121›Full record

ArticleFrontiers in pharmacology2018

Resveratrol Delivery by Albumin Nanoparticles Improved Neurological Function and Neuronal Damage in Transient Middle Cerebral Artery Occlusion Rats.

Huae Xu, Ye Hua, Jie Zhong, Xiaolin Li, Wei Xu, Yingyuan Cai, Yukang Mao, Xiaowei Lu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Effect and mechanisms of resveratrol in animal models of ischemic stroke: A systematic review and Bayesian meta-analysis.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
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  12. Potential Adverse Effects of Resveratrol: A Literature Review.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Huae XuSchool of Pharmacy, Nanjing Medical University, Nanjing, China.
Ye HuaDepartment of Neurology, The Affiliated Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.
Jie ZhongSchool of Foreign Languages, Nanjing University of Finance and Economics, Nanjing, China.
Xiaolin LiDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wei XuDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yingyuan CaiDepartment of Geriatric Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yukang MaoDepartment of Medical Image Science, Xuzhou Medical University, Xuzhou, China.
Xiaowei LuDepartment of Geriatric Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNNanjing University of Finance and Economics · CNWuxi People's Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human serum albumin (HSA) is an intrinsic protein and important carrier that transports endogenous as well as exogenous substances. It is demonstrated in this study that the regional accumulation of albumin in the ischemia-reperfusion (I/R) brain may lead in the application of HSA based nanoparticles in the study of cerebral I/R injury. Resveratrol (RES) is potential in the treatment of cerebral I/R injury but is restricted for its water insolubility and short half-life

Indexed as

cerebralhuman serum albuminischemia-reperfusionnanoparticleresveratrol

Identifiers

PMID30564121
PMCPMC6288361
OpenAlexW2903527383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.