ArticlemBio2018
CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII.
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In one paragraph
Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
What it found
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Who cites it
34 citing papers in PubMed, 49 citations in OpenAlex.
- The GlyGly-CTERM domain functions as an independent motif that targets proteins to rhombosortase inJournal of bacteriology · 2026Article
- Capsular polysaccharides of Acinetobacter baumannii modulate antimicrobial resistance and innate immune response.Scientific reports · 2026Article
- The GlyGly-CTERM domain functions as an independent motif that targets proteins to rhombosortase inbioRxiv : the preprint server for biology · 2026Article
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- Targeting inflammasome, IL-1β, and coagulation in melioidosis.Frontiers in microbiology · 2026Review
- The Type II Secretion System Utilizes AsmA-like Protein GspN to Facilitate Transport of Lipoproteins to the Cell Surface inbioRxiv : the preprint server for biology · 2025Article
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- Augmented insights and minor adjustments to the role of adhesin proteins inInfection and immunity · 2025Article
- Activation of the Coagulation Cascade as a Universal Danger Sign.Current issues in molecular biology · 2025Review
- Pathogenicity and virulence ofVirulence · 2024Review
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- Pathophysiological dynamics in the contact, coagulation, and complement systems during sepsis: Potential targets for nafamostat mesilate.Journal of intensive medicine · 2024Review
- The type II secretion system as an underappreciated and understudied mediator of interbacterial antagonism.Infection and immunity · 2024Review
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- Treatment and Management ofInfection and drug resistance · 2024Review
- Virulence Factors and Pathogenicity Mechanisms ofAntibiotics (Basel, Switzerland) · 2023Review
- Copper Forms a PPII Helix-Like Structure with the Catalytic Domains of Bacterial Zinc Metalloproteases.Inorganic chemistry · 2023Article
- Talaromyces marneffei suppresses macrophage inflammation by regulating host alternative splicing.Communications biology · 2023Article
- Uncovering the Secretion Systems ofAntibiotics (Basel, Switzerland) · 2023Review
- Review
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Ursula WaackDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Mark WarnockDepartment of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Andrew YeeLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
Zachary HuttingerLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
Sara SmithDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Ayush KumarDepartment of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-6395-7932
Alban DerouxGrenoble Alpes University Hospital, Grenoble, France.
David GinsburgLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
Harry L T MobleyDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Daniel A LawrenceDepartment of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Maria SandkvistDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA mariasan@umich.edu.
University of Michigan · USHoward Hughes Medical Institute · USUniversité Grenoble Alpes · FRUniversity of Manitoba · CA
Funding
Unraveling the role of tPA in the neurovascular unitR01HL055374 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti, Daniel A Lawrence · 1995 to 2026
$8.6MThe Molecular Genetics of HemostasisR35HL135793 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GINSBURG, DAVID · 2017 to 2023
$4.1MOrganization and Function of a Type II Secretion ComplexR01AI049294 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANDKVIST, MARIA B · 2002 to 2012
$2.9MMolecular Mechanisms of Protein Sorting by the Type II Secretion SystemR01AI137085 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANDKVIST, MARIA B · 2018 to 2022
$2.0MTraining Program in Translational Cardiovascular Research and EntrepreneurshipT32HL125242 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MICHELE, DANIEL E · 2015 to 2024
$1.9MGenome-wide identification of virulence genes in Acinetobacter baumannii in vivoR21AI107184 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 2014 to 2015
$428kOrganization and function of a type II secretion complexR56AI049294 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANDKVIST, MARIA B · 2015 to 2015
$393kHoward Hughes Medical InstituteNHLBI NIH HHS R01 HL055374NHLBI NIH HHS R35 HL135793NHLBI NIH HHS T32 HL125242NIAID NIH HHS R01 AI049294NIAID NIH HHS R01 AI137085NIAID NIH HHS R21 AI107184NIAID NIH HHS R56 AI049294
Abstract
Antibiotic-resistant
Indexed as
Acinetobacter baumanniiAngioedemas, HereditaryAnimalsBacterial ProteinsBlood CoagulationFactor XIIFemaleHumansMetalloproteasesMiceMice, Inbred CBAMiddle AgedMutationPartial Thromboplastin TimeProthrombin TimeVirulence FactorsBacterial ProteinsFactor XIIMetalloproteasesVirulence FactorsAcinetobacter baumanniiCpaAfactor XIImetalloproteaseO-linked glycosylationthrombosistype II secretion system
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.