Evidence map›Paper›PMID 30563899›Full record

ArticlemBio2018

A New Mechanism for Ribosome Rescue Can Recruit RF1 or RF2 to Nonstop Ribosomes.

Tyler D P Goralski, Girish S Kirimanjeswara, Kenneth C Keiler

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. AACS infectious diseases · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Ribosome Rescue Pathways in Bacteria.Frontiers in microbiology · 2021
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tyler D P GoralskiDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Girish S KirimanjeswaraDepartment of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0002-9216-1105
Kenneth C KeilerDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA kck11@psu.edu.ORCID 0000-0001-8753-335X
Pennsylvania State University · US

Funding

Physiology of ribosome rescue in bacteriaR01GM121650 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI KEILER, KENNETH C · 2017 to 2025
$3.8M
Mechanism of Antibody-mediated Immunity against F. tularensisR00AI077917 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI KIRIMANJESWARA, GIRISH S · 2011 to 2012
$490k
NIAID NIH HHS R00 AI077917NIGMS NIH HHS R01 GM121650
6 · The paper itself

Abstract

Bacterial ribosomes frequently translate to the 3' end of an mRNA without terminating at an in-frame stop codon. In all bacteria studied to date, these "nonstop" ribosomes are rescued using

Indexed as

Bacterial ProteinsFrancisella tularensisModels, MolecularProtein BindingProtein BiosynthesisRibosomesRNA-Binding ProteinsBacterial ProteinsRNA-Binding ProteinsFrancisella tularensisribosomesTn-seqtrans-translation

Identifiers

PMID30563899
PMCPMC6299226
OpenAlexW2899776329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.