Evidence map›Paper›PMID 30563860›Full record

ArticleGenetics2019

A Novel Role for α-Importins and Akirin in Establishment of Meiotic Sister Chromatid Cohesion in

Richard Bowman, Nathan Balukof, Talitha Ford, Sarit Smolikove

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Richard BowmanDepartment of Biology, University of Iowa, Iowa City, Iowa 52240.ORCID 0000-0002-3985-5482
Nathan BalukofDepartment of Biology, University of Iowa, Iowa City, Iowa 52240.
Talitha FordDepartment of Biology, University of Iowa, Iowa City, Iowa 52240.ORCID 0000-0002-0146-2966
Sarit SmolikoveDepartment of Biology, University of Iowa, Iowa City, Iowa 52240 sarit-smolikove@uiowa.edu.ORCID 0000-0003-0062-3606
University of Iowa · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

During meiotic prophase I, sister chromatid cohesion is established in a way that supports the assembly of the synaptonemal complex (SC). The SC connects homologous chromosomes, directing meiotic recombination to create crossovers. In this paper, we identify two proteins that cooperate to import and load meiotic cohesins, thus indirectly promoting SC assembly. AKIR-1 is a protein with a previously identified meiotic role in SC disassembly.

Indexed as

MeiosisAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsChromatidsGerm CellsKaryopherinsMutationProtein BindingSister Chromatid ExchangeSynaptonemal ComplexAkir-1 protein, C elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsHIM-8 protein, C elegansIMA-2 protein, C elegansKaryopherinsAKIR-1AkirinCOH-3/4cohesincohesionIMA-2importinmeiosisREC-8synaptonemal complex

Identifiers

PMID30563860
PMCPMC6366927
OpenAlexW2905009436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.