Evidence map›Paper›PMID 30563614›Full record

ArticleThe American journal of cardiology2019

Effect of Obesity on Left Atrial Strain in Persons Aged 35-55 Years (The Asklepios Study).

Julio A Chirinos, Mayank Sardana, Vaibhav Satija, Thierry C Gillebert, Marc L De Buyzere, Jugal Chahwala, Dirk De Bacquer, Patrick Segers, Ernst R Rietzschel, Asklepios investigators

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 57 citations in OpenAlex.

  1. Trial
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Glycemic status and left atrial structure and function in adults with metabolic syndrome and overweight-obesity.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Atrial fibrillation substrate and impaired left atrial function: a cardiac MRI study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Julio A ChirinosUniversity of Pennsylvania Perelman School of Medicine and Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Ghent University, Ghent, Belgium. Electronic address: Julio.chirinos@uphs.upenn.edu.
Mayank SardanaUniversity of California San Francisco, San Francisco, California.
Vaibhav SatijaUniversity of Pennsylvania Perelman School of Medicine and Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Thierry C GillebertGhent University, Ghent, Belgium; Ghent University Hospital, Ghent, Belgium.
Marc L De BuyzereGhent University, Ghent, Belgium; Ghent University Hospital, Ghent, Belgium.
Jugal ChahwalaUniversity of Pennsylvania Perelman School of Medicine and Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Dirk De BacquerGhent University, Ghent, Belgium.
Patrick SegersGhent University, Ghent, Belgium; Biofluid, Tissue, and Solid Mechanics for Medical Applications, IBiTech, iMinds Future Health Department, Ghent University, Ghent, Belgium.
Ernst R RietzschelGhent University, Ghent, Belgium; Ghent University Hospital, Ghent, Belgium.
Asklepios investigators
Ghent University Hospital · BEHospital of the University of Pennsylvania · USUniversity of California, San Francisco · US

Funding

Efficacy of Potassium Nitrate in Heart Failure with Preserved Ejection FractionR01HL121510 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHIRINOS MEDINA, JULIO ALONSO · 2015 to 2019
$3.1M
NHLBI NIH HHS R01 HL121510
6 · The paper itself

Abstract

Obesity increases the risk of heart failure and atrial fibrillation. Left atrial (LA) dysfunction is increasingly recognized as a mediator of cardiovascular disease. Early effects of obesity on LA function have not been examined in large population samples. We quantified LA strain and strain rate (SR) through speckle tracking echocardiography in 1,531 middle-aged community-based participants enrolled in the Asklepios study. We compared LA function between individuals with body mass index (BMI) < 25 kg/m

Indexed as

Atrial RemodelingAdultAtrial FibrillationAtrial Function, LeftBody Mass IndexEchocardiography, DopplerFemaleHealthy VolunteersHeart AtriaHeart FailureHumansMagnetic Resonance Imaging, CineMaleMiddle AgedObesityRisk Factors

Identifiers

PMID30563614
PMCPMC6369023
OpenAlexW2902336666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.