ArticleBMC plant biology2018
Comparative physiological responses and transcriptome analysis reveal the roles of melatonin and serotonin in regulating growth and metabolism in Arabidopsis.
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Tryptophan metabolism and plant health: mechanisms of action and application prospects.Frontiers in plant science · 2026Pooled it
- Multi-Level Physiological and Metabolomic Responses ofPlants (Basel, Switzerland) · 2026Article
- Synergistic melatonin and myo-inositol application reinforces antioxidant defence, osmotic homeostasis, and membrane stability in Western Himalayan apple rootstocks under drought stress.BMC plant biology · 2026Article
- Foliar application of allantoin and serotonin mitigates salinity stress in bitter melon (Momordica charantia L.).Scientific reports · 2026Article
- Article
- Exogenous melatonin alleviates copper stress in apple rootstock M9T337 by regulating the antioxidant system and carbon-nitrogen metabolism.Frontiers in plant science · 2026Article
- Serotonin modulation of metabolism and stress response in Pseudomonas fluorescens.BMC biology · 2025Article
- Melatonin at Crossroads with Phytohormones: Interactions Under High Light Stress.International journal of molecular sciences · 2025Article
- Photoreceptors Are Involved in Antioxidant Effects of Melatonin Under High Light inAntioxidants (Basel, Switzerland) · 2025Article
- Rice Cytochrome P450 Protein CYP71P1 Is Required for Heat Stress Tolerance by Regulating Serotonin Biosynthesis and ROS Homeostasis.Plants (Basel, Switzerland) · 2025Article
- The Effect of Exogenous Melatonin on the Photosynthetic Characteristics ofPlants (Basel, Switzerland) · 2025Article
- Effects of tryptamine on duckweed growth.Frontiers in plant science · 2025Article
- Relationship between the GABA Pathway and Signaling of Other Regulatory Molecules.International journal of molecular sciences · 2024Review
- Enhanced In Vitro Plant Morphogenesis of Tobacco: Unveiling Indoleamine-Modulated Adaptogenic Properties of Tulsi (Plants (Basel, Switzerland) · 2024Article
- Integrated multi-omic approach reveals the effect of a Graminaceae-derived biostimulant and its lighter fraction on salt-stressed lettuce plants.Scientific reports · 2024Article
- Why did glutamate, GABA, and melatonin become intercellular signalling molecules in plants?eLife · 2023Review
- Glucoraphanin and sulforaphane biosynthesis by melatonin mediating nitric oxide in hairy roots of broccoli (Brassica oleracea L. var. italica Planch): insights from transcriptome data.BMC plant biology · 2022Article
- Rhizosphere melatonin application reprograms nitrogen-cycling related microorganisms to modulate low temperature response in barley.Frontiers in plant science · 2022Article
- The Plant-Stress Metabolites, Hexanoic Aacid and Melatonin, Are Potential "Vaccines" for Plant Health Promotion.The plant pathology journal · 2021Review
- Melatonin and Phytomelatonin: Chemistry, Biosynthesis, Metabolism, Distribution and Bioactivity in Plants and Animals-An Overview.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMelatonin and serotonin are well-known signaling molecules that mediate multiple physiological activities in plants, including stress defense, growth, development, and morphogenesis, but their underlying mechanisms have not yet been thoroughly elucidated. In this study, we investigated the roles of melatonin and serotonin in modulating plant growth and defense by integrating physiological and transcriptome analyses in Arabidopsis.
resultsModerate concentrations of melatonin and serotonin did not affect primary root (PR) growth but markedly induced lateral root (LR) formation. Both melatonin and serotonin locally induced the expression of the cell-wall-remodeling-related genes LBD16 and XTR6, thereby inducing LR development. Our data support the idea that melatonin and serotonin lack any auxin-like activity. Treatment with 50 μM serotonin significantly improved PSII activity, and the transcriptome data supported this result. Melatonin and serotonin slightly affected glycolysis and the TCA cycle; however, they markedly regulated the catabolism of several key amino acids, thereby affecting carbon metabolism and energy metabolism. Melatonin and serotonin improved iron (Fe) deficiency tolerance by inducing Fe-responsive gene expression.
conclusionsOverall, our results from the physiological and transcriptome analyses reveal the roles of melatonin and serotonin in modulating plant growth and stress responses and provide insight into novel crop production strategies using these two phytoneurotransmitters.
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Registered trials
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