ArticleBMC plant biology2018
Anthocyanin accumulation correlates with hormones in the fruit skin of 'Red Delicious' and its four generation bud sport mutants.
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 94 citations in OpenAlex.
- Molecular Mechanisms and Regulation of Anthocyanin Biosynthesis in Rosaceae Fruits: A Review.Food science & nutrition · 2026Review
- Mevalonate kinase represses anthocyanin biosynthesis via sucrose transporters and gibberellin synthesis pathways in arabidopsis.Plant cell reports · 2026Article
- Combined Transcriptome and Metabolome Analysis of the Quality Change Mechanism of the 'Pingguoli' Pear with a Large-Fruited Bud Mutation.Plants (Basel, Switzerland) · 2026Article
- MEVALONATE KINASE represses anthocyanin biosynthesis via sucrose transporters and gibberellin synthesis pathways in Arabidopsis.Research square · 2025Article
- Article
- CYP98A monooxygenases: a key enzyme family in plant phenolic compound biosynthesis.Horticulture research · 2025Article
- HMGR Modulates Strawberry Fruit Coloration and Aroma Through Regulating Terpenoid and Anthocyanin Pathways.Foods (Basel, Switzerland) · 2025Article
- Preliminary Analysis of the Formation Mechanism of Floret Color in Broccoli (Plants (Basel, Switzerland) · 2025Article
- Integrated metabolomics and transcriptomics unravel the biosynthZaesis mechanism of anthocyanin in postharvest red raspberry (Frontiers in plant science · 2025Article
- Multi-omics analysis reveals key regulatory defense pathways and genes involved in salt tolerance of rose plants.Horticulture research · 2024Article
- Hypermethylation in the promoter regions of flavonoid pathway genes is associated with skin color fading during 'Daihong' apple fruit development.Horticulture research · 2024Article
- Multi-omics analysis provides new insights into the changes of important nutrients and fructose metabolism in loquat bud sport mutant.Frontiers in plant science · 2024Article
- Metabolome integrated with transcriptome reveals the mechanism of three different color formations inFrontiers in plant science · 2024Article
- Whole-genome resequencing and transcriptome analyses of four generation mutants to reveal spur-type and skin-color related genes in apple (Malus domestica Borkh. Cv. Red delicious).BMC plant biology · 2023Article
- Article
- Environmental Stimuli and Phytohormones in Anthocyanin Biosynthesis: A Comprehensive Review.International journal of molecular sciences · 2023Review
- The Chemical Composition and Transcriptome Analysis Reveal the Mechanism of Color Formation in Tea (International journal of molecular sciences · 2023Article
- Integrative Analysis of Fruit Quality and Anthocyanin Accumulation of PlumPlants (Basel, Switzerland) · 2023Article
- Genome-Wide Identification of bHLH Transcription Factor Family inPlants (Basel, Switzerland) · 2023Article
- Transcriptomic profiling analysis to identify genes associated with PA biosynthesis and insolubilization in the late stage of fruit development in C-PCNA persimmon.Scientific reports · 2022Article
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundBud sport mutants of apple (Malus domestica Borkh.) trees with a highly blushed colouring pattern are mainly caused by the accumulation of anthocyanins in the fruit skin. Hormones are important factors modulating anthocyanin accumulation. However, a good understanding of the interplay between hormones and anthocyanin synthesis in apples, especially in mutants at the molecular level, remains elusive. Here, physiological and comparative transcriptome approaches were used to reveal the molecular basis of color pigmentation in the skin of 'Red Delicious' (G0) and its mutants, including 'Starking Red' (G1), 'Starkrimson' (G2), 'Campbell Redchief' (G3) and 'Vallee spur' (G4).
resultsPigmentation in the skin gradually proliferated from G0 to G4. The anthocyanin content was higher in the mutants than in 'Red Delicious'. The activation of early phenylpropanoid biosynthesis genes, including ASP3, PAL, 4CL, PER, CHS, CYP98A and F3'H, was more responsible for anthocyanin accumulation in mutants at the color break stage. In addition, IAA and ABA had a positive regulatory effect on the synthesis of anthocyanins, while GA had the reverse effect. The down-regulation of AACT1, HMGS, HMGR, MVK, MVD2, IDI1 and FPPS2 involved in terpenoid biosynthesis influences anthocyanin accumulation by positively regulating transcripts of AUX1 and SAUR that contribute to the synthesis of IAA, GID2 to GA, PP2C and SnRK2 to ABA. Furthermore, MYB and bHLH members, which are highly correlated (r=0.882-0.980) with anthocyanin content, modulated anthocyanin accumulation by regulating the transcription of structural genes, including CHS and F3'H, involved in the flavonoid biosynthesis pathway.
conclusionsThe present comprehensive transcriptome analyses contribute to the understanding of the the relationship between hormones and anthocyanin synthesis as well as the molecular mechanism involved in apple skin pigmentation.
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