Evidence map›Paper›PMID 30563229›Full record

ArticleSensors (Basel, Switzerland)2018

The Application of ATR-FTIR Spectroscopy and the Reversible DNA Conformation as a Sensor to Test the Effectiveness of Platinum(II) Anticancer Drugs.

Khansa Al-Jorani, Anja Rüther, Miguela Martin, Rukshani Haputhanthri, Glen B Deacon, Hsiu Lin Li, Bayden R Wood

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. Molecular Spectroscopic Markers of DNA Damage.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Khansa Al-JoraniCentre for Biospectroscopy and School of Chemistry, Monash University, Clayton, VIC 3800, Australia. khansa.al-jorani@monash.edu.
Anja RütherCentre for Biospectroscopy and School of Chemistry, Monash University, Clayton, VIC 3800, Australia. anja.ruether@monash.edu.
Miguela MartinCentre for Biospectroscopy and School of Chemistry, Monash University, Clayton, VIC 3800, Australia. miguela.martin@monash.edu.ORCID 0000-0001-8653-692X
Rukshani HaputhanthriCentre for Biospectroscopy and School of Chemistry, Monash University, Clayton, VIC 3800, Australia. rukshaniH@slintec.lk.
Glen B DeaconSchool of Chemistry, Monash University, Clayton, VIC 3800, Australia. glen.deacon@monash.edu.ORCID 0000-0002-6966-6121
Hsiu Lin LiSchool of Chemistry, Monash University, Clayton, VIC 3800, Australia. hsiu.li@unsw.edu.au.ORCID 0000-0002-6966-6121
Bayden R WoodCentre for Biospectroscopy and School of Chemistry, Monash University, Clayton, VIC 3800, Australia. Bayden.Wood@monash.edu.ORCID 0000-0003-3581-447X
Monash University · AUUNSW Sydney · AU

Funding

Australian Research Council FT120100926
6 · The paper itself

Abstract

Platinum(II) complexes have been found to be effective against cancer cells. Cisplatin curbs cell replication by interacting with the deoxyribonucleic acid (DNA), reducing cell proliferation and eventually leading to cell death. In order to investigate the ability of platinum complexes to affect cancer cells, two examples from the class of polyfluorophenylorganoamidoplatinum(II) complexes were synthesised and tested on isolated DNA. The two compounds

Indexed as

Biosensing TechniquesNucleic Acid ConformationAnimalsAntineoplastic AgentsCattleCisplatinDNAPlatinumPrincipal Component AnalysisSpectroscopy, Fourier Transform InfraredAntineoplastic Agentscalf thymus DNACisplatinDNAPlatinumDNAIRplatinum

Identifiers

PMID30563229
PMCPMC6308638
OpenAlexW2896593870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.