Evidence map›Paper›PMID 30563054›Full record

ArticleInternational journal of molecular sciences2018

Anti-Inflammatory Effect of IL-37-Producing T-Cell Population in DSS-Induced Chronic Inflammatory Bowel Disease in Mice.

Zhangbo Chen, Shijun Wang, Lingyun Li, Zhong Huang, Ke Ma

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhangbo ChenDepartment of Immunology, Shenzhen University School of Medicine, Nanhai Ave. 3688, Shenzhen 518060, China. chzb@szu.edu.cn.
Shijun WangShandong Co-Innovation Center of Classic TCM formula, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. wsj@sdutcm.edu.cn.
Lingyun LiDepartment of Immunology, Shenzhen University School of Medicine, Nanhai Ave. 3688, Shenzhen 518060, China.
Zhong HuangDepartment of Immunology, Shenzhen University School of Medicine, Nanhai Ave. 3688, Shenzhen 518060, China. hzh081@szu.edu.cn.
Ke MaShandong Co-Innovation Center of Classic TCM formula, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. make19880710@163.com.ORCID 0000-0003-4942-9281
Shenzhen University · CNShandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory disease that is thought to arise in part from abnormal adaptive immune responses against intestinal microbiota. T lymphocytes play significant roles in triggering mucosal inflammation and/or maintaining gut immune homeostasis. It has been demonstrated that IL-37 expresses in a variety of cells and exerts a protective function involved in both innate immunity and adaptive immunity. In the present study, a population of IL-37-producing T-cells was detected in the spleen and mesenteric lymph nodes (MLNs) in IL-37

Indexed as

Adoptive TransferAnimalsChronic DiseaseDextran SulfateInflammatory Bowel DiseasesInterferon-gammaInterleukin-1Interleukin-10MiceMice, TransgenicT-LymphocytesDextran SulfateIFNG protein, mouseIL10 protein, mouseInterferon-gammaInterleukin-1Interleukin-10chronic IBDIL-37T lymphocyte

Identifiers

PMID30563054
PMCPMC6321614
OpenAlexW2901988977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.