Evidence map›Paper›PMID 30562976›Full record

ArticleJournal of clinical medicine2018

Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological Phenotype Similar to Obese Patients.

Lukas Denkmayr, Alexandra Feldman, Lars Stechemesser, Sebastian K Eder, Stephan Zandanell, Michael Schranz, Michael Strasser, Ursula Huber-Schönauer, Stephan Buch, Jochen Hampe and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Lukas DenkmayrFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. l.denkmayr@salk.at.
Alexandra FeldmanFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. a.feldman@salk.at.
Lars StechemesserFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. l.stechemesser@salk.at.
Sebastian K EderFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. sebastian.eder@gmail.com.
Stephan ZandanellFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. s.zandanell@salk.at.
Michael SchranzFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. m.schranz@salk.at.
Michael StrasserFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. m.strasser@salk.at.
Ursula Huber-SchönauerDepartment of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, 5110 Oberndorf, Austria. huber.schoenauer@gmail.com.
Stephan BuchDepartment of Gastroenterology and Hepatology, Internal Medicine, University Hospital Dresden, 01307 Dresden, Germany. Stephan.buch@uniklinikum-dresden.de.
Jochen HampeDepartment of Gastroenterology and Hepatology, Internal Medicine, University Hospital Dresden, 01307 Dresden, Germany. Jochen.Hampe@uniklinikum-dresden.de.
Bernhard PaulweberFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. B.Paulweber@salk.at.
Carolin LacknerInstitute of Pathology, Medical University of Graz, 8010 Graz, Austria. karoline.lackner@medunigraz.at.
Heike HaufeInstitute of Pathology, Paracelsus Medical University, 5020 Salzburg, Austria. h.haufe@salk.at.
Karl SotlarInstitute of Pathology, Paracelsus Medical University, 5020 Salzburg, Austria. k.sotlar@salk.at.
Christian DatzObesity Research Unit, Paracelsus Medical University, 5020 Salzburg, Austria. c.datz@kh-oberndorf.at.ORCID 0000-0001-7838-4532
Elmar AignerFirst Department of Medicine, Paracelsus Medical University, 5020 Salzburg, Austria. e.aigner@salk.at.
Paracelsus Medical University · ATMedical University of Graz · AT

Funding

PMU Research Fund PMU-FFF E-13/17/086-AIG and E-15/21/108-AIE
6 · The paper itself

Abstract

A small proportion of lean patients develop non-alcoholic fatty liver disease (NAFLD). We aimed to report the histological picture of lean NAFLD in comparison to overweight and obese NAFLD patients. Biopsy and clinical data from 466 patients diagnosed with NAFLD were stratified to groups according to body mass index (BMI): lean (BMI ≤ 25.0 kg/m²,

Indexed as

fatty liverinsulin resistancemetabolic syndromenon-alcoholicobesity

Identifiers

PMID30562976
PMCPMC6306845
OpenAlexW2904837342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.