Evidence map›Paper›PMID 30562925›Full record

ArticleInternational journal of molecular sciences2018

Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin Expression/Secretion in MG-63 Osteoblastic Cells.

Mei-Chi Chang, Yunn-Jy Chen, Yun-Chia Lian, Bei-En Chang, Chih-Chia Huang, Wei-Ling Huang, Yu-Hwa Pan, Jiiang-Huei Jeng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Intestinal-Bone Axis Mediated byMicroorganisms · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Hypomethylation of theInternational journal of molecular sciences · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. More Than Just a Periodontal Pathogen -the Research Progress onFrontiers in cellular and infection microbiology · 2022
    Review
  15. Review
  16. Association of gut microbiomes with lung and esophageal cancer: a pilot study.World journal of microbiology & biotechnology · 2021
    Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Mei-Chi ChangChang Gung University of Science and Technology, Kwei-Shan, Taoyuan 333, Taiwan. mcchang@mail.cgust.edu.tw.
Yunn-Jy ChenSchool of Dentistry and Department of Dentistry, National Taiwan University Hospital and National Taiwan University Medical College, Taipei 100, Taiwan. chenyj@ntu.edu.tw.
Yun-Chia LianDepartment of Dentistry, Chang Gung Memorial Hospital, Taipei Branch, 6th Floor, 199, Tung-Hwa North Road, Taipei 105, Taiwan. yunyun445@cgmh.org.tw.
Bei-En ChangGraduate Institute of Oral Biology, National Taiwan University Medical College, Taipei 100, Taiwan. beien@ntu.edu.tw.
Chih-Chia HuangDepartment of Dentistry, Cardinal Tien Hospital, New Taipei City 234, Taiwan. frank554@ms13.hinet.net.
Wei-Ling HuangDepartment of Dentistry, Chang Gung Memorial Hospital, Taipei Branch, 6th Floor, 199, Tung-Hwa North Road, Taipei 105, Taiwan. weiwei0110@hotmail.com.
Yu-Hwa PanDepartment of Dentistry, Chang Gung Memorial Hospital, Taipei Branch, 6th Floor, 199, Tung-Hwa North Road, Taipei 105, Taiwan. Shalom.dc@msa.hinet.net.
Jiiang-Huei JengSchool of Dentistry and Department of Dentistry, National Taiwan University Hospital and National Taiwan University Medical College, Taipei 100, Taiwan. jhjeng@ntu.edu.tw.
Chang Gung Memorial Hospital · TWNational Taiwan University Hospital · TWCardinal Tien Hospital · TWChang Gung University · TWNational Taiwan University · TW

Funding

Chang Gung Memorial Hospital CMRPF1H0061, CMRPF1F0071, CMRPF1G0101, CMRPF1G0102, CMRPF3E0021, CMRPF3E0022, CMRPF3E0023, NMRPF3C0091, NMRPF3C0061, CMRPG1B0031, CMRPF170053, NMRPF370033, CMRPF3E0021, NMRPF3B0071, NMRPF3E0041, NMRPF3E0042, NMRPF3E0043, NMRPF3C0093, NMRPF3H0071, NMRPF3H0Ministry of Science and Technology, Taiwan NSC102-2314-B-255-003-MY2, NSC102-2628-B-255-001-MY3, NSC101-2320-B-255-002, NSC-100-2314-B-002-094, NSC-101-2320- B-255-002, MOST104-2314-B-255-010-MY3, MOST106-2314-B-002-034-MY2, and MOST106- 2314-B-002-033-MY2National Taiwan University Hospital NTUH 101-001937, NTUH102-002259, NTUH101-S1862 & NTUH102-S2180, NTUH103-S2368, NTUH104-S2658, NTUH106-S3467, NTUH106-UN-001
6 · The paper itself

Abstract

Butyric acid as a histone deacetylase (HDAC) inhibitor is produced by a number of periodontal and root canal microorganisms (such as

Indexed as

AcetylationButyratesCell LineDental Pulp CavityGene Expression RegulationHistonesHumansIsoprostanesOsteoblastsOsteoprotegerinPeriodontitisRANK LigandButyratesHistonesIsoprostanesOsteoprotegerinRANK LigandTNFRSF11B protein, humanTNFSF11 protein, humanbone resorptionbutyric acidHDAC inhibitorosteoblastsosteoprotegerin/RANKLperiodontal/root canal pathogens

Identifiers

PMID30562925
PMCPMC6321057
OpenAlexW2905220641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.