Evidence map›Paper›PMID 30562397›Full record

ArticlePloS one2018

Improvement of the performance of survival prediction in the ageing blunt trauma population: A cohort study.

Leonie de Munter, Nancy C W Ter Bogt, Suzanne Polinder, Charlie A Sewalt, Ewout W Steyerberg, Mariska A C de Jongh

Abstract readValidation Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. RISC II is superior to TRISS in predicting 30-day mortality in blunt major trauma patients in Hong Kong.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leonie de MunterDepartment Trauma TopCare, Elisabeth-TweeSteden Hospital (ETZ Ziekenhuis), Tilburg, the Netherlands.ORCID 0000-0001-6573-2032
Nancy C W Ter BogtNetwork Emergency Care Euregio, Enschede, the Netherlands.
Suzanne PolinderDepartment of Public Health, Erasmus Medical Centre, Rotterdam, the Netherlands.
Charlie A SewaltDepartment of Public Health, Erasmus Medical Centre, Rotterdam, the Netherlands.
Ewout W SteyerbergDepartment of Public Health, Erasmus Medical Centre, Rotterdam, the Netherlands.
Mariska A C de JonghDepartment Trauma TopCare, Elisabeth-TweeSteden Hospital (ETZ Ziekenhuis), Tilburg, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe overestimation of survival predictions in the ageing trauma population results in negative benchmark numbers in hospitals that mainly treat elderly patients. The aim of this study was to develop and validate a modified Trauma and Injury Severity Score (TRISS) for accurate survival prediction in the ageing blunt trauma population.

methodsThis retrospective study was conducted with data from two Dutch Trauma regions. Missing values were imputed. New prediction models were created in the development set, including age (continuous or categorical) and Anesthesiologists Physical Status (ASA). The models were externally validated. Subsets were created based on age (≥75 years) and the presence of hip fracture. Model performance was assessed by proportion explained variance (Nagelkerke R2), discrimination (Area Under the curve of the Receiver Operating Characteristic, AUROC) and visually with calibration plots. A final model was created based on both datasets.

resultsNo differences were found between the baseline characteristics of the development dataset (n = 15,530) and the validation set (n = 15,504). The inclusion of ASA in the prediction models showed significant improved discriminative abilities in the two subsets (e.g. AUROC of 0.52 [95% CI: 0.46, 0.58] vs. 0.74 [95% CI: 0.69, 0.78] for elderly patients with hip fracture) and an increase in the proportion explained variance (R2 = 0.32 to R2 = 0.35 in the total cohort). The final model showed high agreement between observed and predicted survival in the calibration plot, also in the subsets.

conclusionsIncluding ASA and age (continuous) in survival prediction is a simple adjustment of the TRISS methodology to improve survival predictions in the ageing blunt trauma population. A new model is presented, through which even patients with isolated hip fractures could be included in the evaluation of trauma care.

Indexed as

AgingTrauma Severity IndicesAgedAged, 80 and overAge FactorsArea Under CurveFemaleHip FracturesHumansMaleMiddle AgedPrognosisRetrospective StudiesROC CurveSurvival AnalysisWounds, Nonpenetrating

Identifiers

PMID30562397
PMCPMC6298684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.