Evidence map›Paper›PMID 30562165›Full record

ArticlePhysiological measurement2019

An active learning framework for enhancing identification of non-artifactual intracranial pressure waveforms.

Murad Megjhani, Ayham Alkhachroum, Kalijah Terilli, Jenna Ford, Clio Rubinos, Julie Kromm, Brendan K Wallace, E Sander Connolly, David Roh, Sachin Agarwal and 4 more

Abstract read
In one paragraph

Article in Physiological measurement, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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  8. Big data and predictive analytics in neurocritical care.Current neurology and neuroscience reports · 2022
    Review
  9. Review
  10. Article
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  12. Neurocritical Care: Bench to Bedside (Eds. Claude Hemphill, Michael James) Integrating and Using Big Data in Neurocritical Care.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Murad MegjhaniDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID 0000-0002-7613-6444
Ayham AlkhachroumDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID 0000-0003-0352-5913
Kalijah TerilliDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID 0000-0003-2198-5147
Jenna FordDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Clio RubinosDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Julie KrommDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Brendan K WallaceDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
E Sander ConnollyDepartment of Neurosurgery, Columbia University Irving Medical Center, New York, NY, United States of America.
David RohDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Sachin AgarwalDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Jan ClaassenDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Raghav PadmanabhanNeogenomics Laboratories, Orange County, CA, United States of America.
Xiao HuDepartment of Physiological Nursing, University of California San Francisco, San Francisco, CA, United States of America.
Soojin ParkDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, United States of America.
Columbia University Irving Medical Center · USNeoGenomics (United States) · USUniversity of California, San Francisco · US

Funding

Multiparametric Prediction of Vasospasm after Subarachnoid HemorrhageK01ES026833 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PARK, SOOJIN · 2015 to 2019
$1.1M
NIEHS NIH HHS K01 ES026833
6 · The paper itself

Abstract

objectiveIntracranial pressure (ICP) is an important and established clinical measurement that is used in the management of severe acute brain injury. ICP waveforms are usually triphasic and are susceptible to artifact because of transient catheter malfunction or routine patient care. Existing methods for artifact detection include threshold-based, stability-based, or template matching, and result in higher false positives (when there is variability in the ICP waveforms) or higher false negatives (when the ICP waveforms lack complete triphasic components but are valid). APPROACH: We hypothesized that artifact labeling of ICP waveforms can be optimized by an active learning approach which includes interactive querying of domain experts to identify a manageable number of informative training examples. MAIN

resultsThe resulting active learning based framework identified non-artifactual ICP pulses with a superior AUC of 0.96 + 0.012, compared to existing methods: template matching (AUC: 0.71 + 0.04), ICP stability (AUC: 0.51 + 0.036) and threshold-based (AUC: 0.5 + 0.02). SIGNIFICANCE: The proposed active learning framework will support real-time ICP-derived analytics by improving precision of artifact-labelling.

Indexed as

Intracranial PressureMachine LearningSignal Processing, Computer-AssistedArtifactsBrain InjuriesFalse Positive ReactionsFemaleHumansMaleMiddle Aged

Identifiers

PMID30562165
PMCPMC6681897
OpenAlexW2903619982

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.