Evidence map›Paper›PMID 30562056›Full record

Trial reportJournal of athletic training2018

Randomized Controlled Trial Evaluating Aerobic Training and Common Sport-Related Concussion Outcomes in Healthy Participants.

Elizabeth F Teel, Johna K Register-Mihalik, Lawrence Gregory Appelbaum, Claudio L Battaglini, Kevin A Carneiro, Kevin M Guskiewicz, Stephen W Marshall, Jason P Mihalik

2 registry-linked trialsOpen access · diamondAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of athletic training, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02872480 nacompletednot on this map

The Effect of ACTIVE Training in Improving Clinical Outcomes in Healthy and Acutely Concussed College-aged Participants

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2016 to 2017Enrolled45ConditionsCerebral ConcussionArmsACTIVE Training
NCT05886400 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effects of Environmental Distractions on SCAT6 Outcomes

TypeinterventionalSponsorIndiana UniversityRan2023 to 2024Enrolled48ConditionsConcussion, Brain, Mild Traumatic Brain InjuryArmsSCAT6, Visual/ Auditory Distraction
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Elizabeth F TeelSchool of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada.
Johna K Register-MihalikDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill.
Lawrence Gregory AppelbaumDepartment of Psychiatry and Behavioral Sciences, Duke University, Durham, NC.
Claudio L BattagliniDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill.
Kevin A CarneiroDepartment of Neurosurgery, University of North Carolina at Chapel Hill.
Kevin M GuskiewiczDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill.
Stephen W MarshallDepartment of Epidemiology, University of North Carolina at Chapel Hill.
Jason P MihalikDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill.
University of North Carolina at Chapel Hill · USDuke University · USMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAerobic exercise interventions are increasingly being prescribed for concussion rehabilitation, but whether aerobic training protocols influence clinical concussion diagnosis and management assessments is unknown.

objectiveTo investigate the effects of a brief aerobic exercise intervention on clinical concussion outcomes in healthy, active participants.

designRandomized controlled clinical trial.

settingLaboratory. PATIENTS OR OTHER

participantsHealthy (uninjured) participants (n = 40) who exercised ≥3 times/week. INTERVENTION(S): Participants were randomized into the acute concussion therapy intervention (ACTIVE) training or nontraining group. All participants completed symptom, cognitive, balance, and vision assessments during 2 test sessions approximately 14 days apart. Participants randomized to ACTIVE training completed six 30-minute exercise sessions that progressed from 60% to 80% of individualized maximal oxygen consumption (V˙o MAIN OUTCOME MEASURE(S): The CNS Vital Signs standardized scores, Vestibular/Ocular Motor Screening near-point convergence distance (cm), and Graded Symptom Checklist, Balance Error Scoring System, and Standardized Assessment of Concussion total scores.

resultsAn interaction effect was found for total symptom score ( P = .01); the intervention group had improved symptom scores between sessions (session 1: 5.1 ± 5.8; session 2: 1.9 ± 3.6). Cognitive flexibility, executive functioning, reasoning, and total symptom score outcomes were better but composite memory, verbal memory, and near-point convergence distance scores were worse at the second session (all P values < .05). However, few changes exceeded the 80% reliable change indices calculated for this study, and effect sizes were generally small to negligible.

conclusionsA brief aerobic training protocol had few meaningful effects on clinical concussion assessment in healthy participants, suggesting that current concussion-diagnostic and -assessment tools remain clinically stable in response to aerobic exercise training. This provides normative data for future researchers, who should further evaluate the effect of ACTIVE training on clinical outcomes among concussed populations. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov : NCT02872480.

Indexed as

Neuropsychological TestsAthletic InjuriesBrain ConcussionExercise TherapyFemaleHealthy VolunteersHumansMaleMemoryOxygen ConsumptionSportsYoung Adultbalancecognitionexercisemild traumatic brain injuriessymptomsvision

Identifiers

PMID30562056
PMCPMC6365060
OpenAlexW2904196588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.