Evidence map›Paper›PMID 30561987›Full record

ReviewBioconjugate chemistry2019

Designed and Evolved Nucleic Acid Nanotechnology: Contrast and Complementarity.

Tulsi Ram Damase, Peter B Allen

Abstract readReview
In one paragraph

Review in Bioconjugate chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tulsi Ram DamaseDepartment of Chemistry , University of Idaho , 001 Renfrew Hall, 875 Perimeter Drive , Moscow , Idaho 83844-2343 , United States.ORCID 0000-0002-6758-9038
Peter B AllenDepartment of Chemistry , University of Idaho , 001 Renfrew Hall, 875 Perimeter Drive , Moscow , Idaho 83844-2343 , United States.ORCID 0000-0003-2461-3285
University of Idaho · US

Funding

Sequence-structure-function relationships in human visual photopigmentsP20GM104420 · NIGMS · UNIVERSITY OF IDAHO · PI VAN LEUVEN, JAMES · 2015 to 2024
$22.9M
NIGMS NIH HHS P20 GM104420
6 · The paper itself

Abstract

In this review, we explore progress on DNA aptamers (evolved DNA), DNA circuits (designed DNA), and the newest projects that integrate both. Designed DNA nanotechnology includes static nanostructures, dynamic nanodevices, and reaction networks (sometimes called DNA circuits). DNA circuits are dynamic DNA reactions that perform computations and sequence-specific amplification. Directed evolution can be used to produce DNA that can recognize specific targets. Aptamers are evolved nucleic acids; they are produced artificially with an in vitro selection process. DNA aptamers are molecular recognition elements made of single-stranded DNA (ssDNA) with the potential to interact with proteins, small molecules, viruses, and even cells. Designed molecular structures can incorporate aptamers for applications with immediate practical impact.

Indexed as

NanotechnologyAptamers, NucleotideNucleic Acid ConformationNucleic Acid HybridizationAptamers, Nucleotide

Identifiers

PMID30561987
PMCPMC6938684
OpenAlexW2903757341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.