ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019
Mass Oral Azithromycin for Childhood Mortality: Timing of Death After Distribution in the MORDOR Trial.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02047981 (Evaluating Impact of Azithromycin Mass Drug Administrations on All-cause Mortality and Antibiotic Resistance), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating Impact of Azithromycin Mass Drug Administrations on All-cause Mortality and Antibiotic Resistance: Mortality Trial
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Secondary Effects from Mass Azithromycin Administration: A Systematic Review and Meta-analysis.The American journal of tropical medicine and hygiene · 2022Pooled it
- Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality.The New England journal of medicine · 2025Trial
- Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens in Niger.Nature communications · 2022Trial
- Prevalence of nasopharyngealThe Lancet. Microbe · 2022Trial
- The Duration of Protection from Azithromycin Against Malaria, Acute Respiratory, Gastrointestinal, and Skin Infections When Given Alongside Seasonal Malaria Chemoprevention: Secondary Analyses of Data from a Clinical Trial in Houndé, Burkina Faso, and Bougouni, Mali.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Trial
- Single-dose azithromycin for child growth in Burkina Faso: a randomized controlled trial.BMC pediatrics · 2021Trial
- Biannual azithromycin distribution and child mortality among malnourished children: A subgroup analysis of the MORDOR cluster-randomized trial in Niger.PLoS medicine · 2020Trial
- Biannual mass azithromycin distributions and malaria parasitemia in pre-school children in Niger: A cluster-randomized, placebo-controlled trial.PLoS medicine · 2019Trial
- Article
- Impact of azithromycin mass drug administration on the antibiotic-resistant gut microbiome in children: a randomized, controlled trial.Gut pathogens · 2022Article
- Cost-Effectiveness of Mass Treatment with Azithromycin for Reducing Child Mortality in Malawi: Secondary Analysis from the MORDOR Trial.The American journal of tropical medicine and hygiene · 2020Article
- Biannual Treatment of Preschool Children with Single Dose Azithromycin to Reduce Mortality: Impact on Azithromycin Resistance in the MORDOR Trial in Tanzania.The American journal of tropical medicine and hygiene · 2020Article
- Longer-Term Assessment of Azithromycin for Reducing Childhood Mortality in Africa.The New England journal of medicine · 2019Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
In a large community-randomized trial, biannual azithromycin distributions significantly reduced postneonatal childhood mortality in sub-Saharan African sites. Here, we present a prespecified secondary analysis showing that much of the protective effect was in the first 3 months postdistribution. Distributing more frequently than biannually could be considered if logistically feasible. Clinical Trials Registration. NCT02047981.
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Registered trials
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