Evidence map›Paper›PMID 30561420›Full record

ArticleActa bio-medica : Atenei Parmensis2018

How and when investigating and treating Helicobacter pylori infection in children.

Marco Manfredi, Federica Gaiani, Stefano Kayali, Barbara Bizzarri, Silvia Iuliano, Roberta Minelli, Gioacchino Leandro, Francesco Di Mario, Gian Luigi De' Angelis

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Microorganisms · 2026
    Article
  2. Review
  3. Children (Basel, Switzerland) · 2022
    Article
  4. Antibiotic Resistance ofHealthcare (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marco ManfrediAzienda USL of Reggio Emilia-IRCCS, Maternal and Child Department, Pediatric Unit, Sant'Anna Hospital, Castelnovo ne' Monti, Reggio Emilia, Italy. marco.manfredi@ausl.re.it.
Federica Gaiani
Stefano Kayali
Barbara Bizzarri
Silvia Iuliano
Roberta Minelli
Gioacchino Leandro
Francesco Di Mario
Gian Luigi De' Angelis
University of Parma · ITGastroenterology Hospital "Saverio de Bellis" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For thousands of years humans have lived in symbiosis with Helicobacter pylori. This infection is acquired mainly during childhood and, despite it represents one of the most common infections in humans, only a minority of infected people may develop health issues and life-threatening diseases. For diagnosing Helicobacter pylori infection in children we can use, at first, non-invasive diagnostic tests, if clinical pattern and/or history are of suspicion. Then, invasive tests i.e. gastroscopy are necessary to confirm the infection. As antibiotics are not widely available in children affected by Helicobacter pylori infection, they should be chosen based on individual antibiotic susceptibility testing obtained by gastric biopsy specimens or the local antibiotic resistance pattern, in empirical treatment is chosen. Test and treat strategy in children should be avoided. In this brief review we summarize how and in which children the infection should be investigate and which the most appropriate eradication treatment should be chosen.

Indexed as

Helicobacter pyloriAmoxicillinAnti-Bacterial AgentsBiopsyChildChild, PreschoolClarithromycinDrug Resistance, MicrobialDrug Therapy, CombinationEndoscopy, Digestive SystemGastritisHelicobacter InfectionsHumansIncidental FindingsMetronidazolePractice Guidelines as TopicAmoxicillinAnti-Bacterial AgentsClarithromycinMetronidazoleProton Pump InhibitorsTinidazole

Identifiers

PMID30561420
PMCPMC6502211
OpenAlexW2986691695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.