Evidence map›Paper›PMID 30561417›Full record

SynthesisActa bio-medica : Atenei Parmensis2018

A non-invasive method for the diagnosis of upper GI diseases.

Alberto Barchi, Chiara Miraglia, Alessandra Violi, Ginevra Cambiè, Antonio Nouvenne, Mario Capasso, Gioacchino Leandro, Tiziana Meschi, Gian Luigi De' Angelis, Francesco Di Mario

Abstract readSystematic Review
In one paragraph

Synthesis in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alberto BarchiDepartment of Medicine and Surgery, University of Parma, Parma, Italy. alberto.barchi@studenti.unipr.it.
Chiara Miraglia
Alessandra Violi
Ginevra Cambiè
Antonio Nouvenne
Mario Capasso
Gioacchino Leandro
Tiziana Meschi
Gian Luigi De' Angelis
Francesco Di Mario

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upper-GI diseases are one of the most relevant issue in primary care. Nowadays they are still responsible for about 100 million ambulatory care visits only in the US. The diagnosis of almost every upper-GI condition is still deputed to invasive tests such as upper gastrointestinal endoscopy, gastroesophageal manometry or radiography. The possibility of analysing serum markers like Pepsinogens I and II, produced by gastric mucosa, in order to assess the functional characteristics of the upper GI tract has spread itself since the 80's especially in the diagnosis of peptic ulcer. The discovery of Helicobacter pylori by Marshall and Warren in 1983 and the scientific consecration of its role in the pathogenesis of gastric cancer and peptic ulcer (crystallized in Peleo Correa's Cascade, 1992), led to an increase importance of non-invasive tests, raising the attention towards the assessment of both immunoglobulins anti-H.p. and Gastrin hormone produced by antral G cells, as an implementation of the panel of gastric markers. This narrative review aims to analyze the huge landscape of non-invasive tests for diagnosis of GI diseases, studying the literature of the recent years.

Indexed as

Diagnostic Techniques, Digestive SystemAntibodies, BacterialBiomarkersDyspepsiaEndoscopy, GastrointestinalEsophageal DiseasesGastrinsHelicobacter InfectionsHelicobacter pyloriHumansPepsinogensStomach DiseasesAntibodies, BacterialBiomarkersgastrin 17GastrinsPepsinogens

Identifiers

PMID30561417
PMCPMC6502204

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.