ReviewActa bio-medica : Atenei Parmensis2018
Conservative treatment of acute appendicitis.
Review in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04462588 (Are the Changes in Immature Granulocyte Count and Percentage Significant in the Decision to Continue Medical Treatment of Uncomplicated Acute Appendicitis Cases), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Are the Changes in Immature Granulocyte Count and Percentage Significant in the Decision to Continue Medical Treatment of Uncomplicated Acute Appendicitis Cases
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-operative management of appendiceal abscess in children: a systematic review.Annals of medicine · 2025Pooled it
- Are the immature granulocyte count and percentage important in continue medical treatment in acute appendicitis? A prospective, randomized, and controlled study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Trial
- Non-operative Management of Uncomplicated Appendicitis: A Review of Indications, Safety, and Clinical Algorithms.Cureus · 2026Review
- Imaging of appendicitis: Computed tomography, magnetic resonance imaging, and ultrasound in diagnosis and management.World journal of gastrointestinal pathophysiology · 2025Review
- Article
- Clinical significance of appendicoliths in conservative treatment of acute complicated appendicitis patients with peri-appendiceal abscess: a single-center retrospective study.Annals of medicine and surgery (2012) · 2024Article
- Applying an explainable machine learning model might reduce the number of negative appendectomies in pediatric patients with a high probability of acute appendicitis.Scientific reports · 2024Article
- Is non-operative treatment of acute appendicitis possible: A narrative review.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2024Review
- Acute Appendicitis Treatment Strategies and Mortality Based on Critical Illness on Admission: An Observational Study.Surgical infections · 2024Observational
- Tryptase in Acute Appendicitis: Unveiling Allergic Connections through Compelling Evidence.International journal of molecular sciences · 2024Article
- Appendectomy in Children and Adolescents.Deutsches Arzteblatt international · 2024Article
- The efficacy of hemoglobin, albumin, lymphocytes, and platelets (HALP) score in signifying acute appendicitis severity and postoperative outcomes.Updates in surgery · 2023Article
- The Vermiform Appendix and Its Pathologies.Cancers · 2023Review
- Predicting Complicated Appendicitis in Children: Pros and Cons of a New Score Combining Clinical Signs, Laboratory Values, and Ultrasound Images (CLU Score).Diagnostics (Basel, Switzerland) · 2023Article
- Association of the Bacteria of the Vermiform Appendix and the Peritoneal Cavity with Complicated Acute Appendicitis in Children.Diagnostics (Basel, Switzerland) · 2023Article
- Effectiveness of pre-operative routine blood tests in predicting complicated acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- The Prognostic Value of Ultrasound Findings in Preoperatively Distinguishing between Uncomplicated and Complicated Types of Pediatric Acute Appendicitis Based on Correlation with Intraoperative and Histopathological Findings.Diagnostics (Basel, Switzerland) · 2022Article
- Risk factors for periappendiceal adhesions in acute appendicitis: a retrospective comparative study.BMC surgery · 2022Article
- Complicated or non-complicated appendicitis? That is the question.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Predictive value of serum sodium level in determining perforated appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute appendicitis has been considered by surgeons a progressive disease leading to perforation for more than 100 years. In the last decades the theories about this concept gained attention, especially in adults. However, appendectomy for acute appendicitis remains the most common urgent/emergent surgical procedure. At present, accumulating evidences are showing the changing in clinical practice towards the non-operative management of several cases of acute appendicitis either non-complicated or complicated. The present review aims to show the literature results regarding the non-operative management of acute appendicitis in non-complicated and in complicated cases.
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Registered trials
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