Evidence map›Paper›PMID 30561392›Full record

ReviewActa bio-medica : Atenei Parmensis2018

Peripheral neuropathy and gastroenterologic disorders: an overview on an underrecognized association.

Carlotta Spagnoli, Francesco Pisani, Francesco Di Mario, Gioacchino Leandro, Federica Gaiani, Gian Luigi De' Angelis, Carlo Fusco

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carlotta SpagnoliChild Neurology Unit, Azienda USL- IRCCS di Reggio Emilia, Reggio Emilia, Italy. drgioacchinoleandro@gmail.com.
Francesco Pisani
Francesco Di Mario
Gioacchino Leandro
Federica Gaiani
Gian Luigi De' Angelis
Carlo Fusco
Azienda Sanitaria Unità Locale di Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and aim of the workAlthough peripheral neuropathies in children are often of genetic origin, acquired causes should be carefully looked for and ruled out also in the pediatric age. Gastroenterological disorders can be complicated by peripheral neuropathy as a result of micronutrients deficiency, drug toxicity or because of shared pathophysiological mechanisms.

methodsIn this descriptive review we sought to give an overview on the most relevant clinical conditions in which peripheral neuropathies are associated with gastro-intestinal disorders or symptoms.

resultsWe describe the clinical, demographic, and electrophysiological features of peripheral neuropathy in three main clinical scenarios: in the context of common gastroenterological disorders (inflammatory bowel and celiac disease), in the context of micronutrients deficiencies arising from malabsorption irrespective of etiology, and in a rare degenerative mitochondrial disorder, mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) disorder.

conclusionsThe association between gastrointestinal and peripheral nervous system symptoms is probably still underrecognized but has to be actively sought, in order to provide prompt diagnosis resulting in optimal care and long-term management with the aim to improve quality of life and, at least in some conditions, try to impact on prognosis.

Indexed as

Antibodies, MonoclonalAntirheumatic AgentsCampylobacter InfectionsCeliac DiseaseChildComorbidityCyclosporineDiet, Gluten-FreeElectrophysiologyGastrointestinal DiseasesGenetic Predisposition to DiseaseGuillain-Barre SyndromeHumansInflammatory Bowel DiseasesIntestinal Pseudo-ObstructionMalnutritionAntibodies, MonoclonalAntirheumatic AgentsCyclosporineMicronutrientsThalidomide

Identifiers

PMID30561392
PMCPMC6502186
OpenAlexW2993017551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.