ArticleJournal of the American Heart Association2018
Preconception Exposure to Fine Particulate Matter Leads to Cardiac Dysfunction in Adult Male Offspring.
Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04974580 (Young Adult Vaping Cessation), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Young Adult Vaping Cessation: A Randomized Trial Examining Phone Coaching, Text-based Digital Intervention, and Nicotine Replacement Therapy
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- A systematic review of evidence for maternal preconception exposure to outdoor air pollution on Children's health.Environmental pollution (Barking, Essex : 1987) · 2023Pooled it
- Cardiopulmonary and Immune Effects of Environmental Particulate Exposures.Physiology (Bethesda, Md.) · 2026Review
- Gestational exposure to PMJournal of advanced research · 2026Article
- Article
- Gestational exposure to micro and nanoplastics differentially impacts cardiac development and function in male and female rats throughout the lifespan.Toxicology and applied pharmacology · 2025Article
- Particulate matter and co-occurring genetic risk induce oxidative stress and cardiac and brain Alzheimer's pathology.Communications biology · 2025Article
- Ambient Air Pollution and Congenital Heart Disease: Updated Evidence and Future Challenges.Antioxidants (Basel, Switzerland) · 2025Review
- Single pulmonary nanopolystyrene exposure in late-stage pregnancy dysregulates maternal and fetal cardiovascular function.Toxicological sciences : an official journal of the Society of Toxicology · 2024Article
- Review
- Neural mechanism facilitating PM2.5-related cardiac arrhythmias through cardiovascular autonomic and calcium dysregulation in a rat model.Scientific reports · 2023Article
- Aging, longevity, and the role of environmental stressors: a focus on wildfire smoke and air quality.Frontiers in toxicology · 2023Review
- Adverse effects of air pollution-derived fine particulate matter on cardiovascular homeostasis and disease.Trends in cardiovascular medicine · 2022Review
- Article
- Paternal long-term PM2.5 exposure causes hypertension via increased renal AT1R expression and function in male offspring.Clinical science (London, England : 1979) · 2021Article
- Particulate Matter-Induced Cardiovascular Dysfunction: A Mechanistic Insight.Cardiovascular toxicology · 2021Review
- Cohort profile: Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO).European journal of epidemiology · 2021Article
- Aspirin Alleviates Particulate Matter Induced Asymptomatic Orchitis of MiceFrontiers in immunology · 2021Article
- Cardiovascular adaptations to particle inhalation exposure: molecular mechanisms of the toxicology.American journal of physiology. Heart and circulatory physiology · 2020Review
- Exercise does not ameliorate cardiac dysfunction in obese mice exposed to fine particulate matter.Life sciences · 2019Article
- Preconception Exposure to Fine Particulate Matter Leads to Cardiac Dysfunction in Adult Male Offspring.Journal of the American Heart Association · 2018Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
10 authors at 3 institutions in 1 country.
Vineeta Tanwar1 Dorothy M. Davis Heart and Lung Research Institute College of Medicine The Ohio State University Columbus OH.
Jeremy M Adelstein1 Dorothy M. Davis Heart and Lung Research Institute College of Medicine The Ohio State University Columbus OH.
Jacob A Grimmer1 Dorothy M. Davis Heart and Lung Research Institute College of Medicine The Ohio State University Columbus OH.
Dane J Youtz1 Dorothy M. Davis Heart and Lung Research Institute College of Medicine The Ohio State University Columbus OH.
Aashish Katapadi3 Medical Student Research Program The Ohio State University College of Medicine Columbus OH.
Benjamin P Sugar3 Medical Student Research Program The Ohio State University College of Medicine Columbus OH.
Michael J Falvo5 Department of Veterans Affairs War Related Illness and Injury Study Center New Jersey Health Care System East Orange NJ.
Lisa A Baer4 Department of Physiology and Cell Biology The Ohio State University College of Medicine Columbus OH.
Kristin I Stanford1 Dorothy M. Davis Heart and Lung Research Institute College of Medicine The Ohio State University Columbus OH.
Loren E Wold1 Dorothy M. Davis Heart and Lung Research Institute College of Medicine The Ohio State University Columbus OH.
The Ohio State University · USLung Institute · USVA New Jersey Health Care System · US
Funding
Mechanisms of exposure-induced tissue functional and pathological changes in a mouse model of Alzheimer's DiseaseR01AG057046 · NIA · OHIO STATE UNIVERSITY · PI COMBS, COLIN K, DEL MONTE, FEDERICA · 2017 to 2021
$4.0MA Novel Role for Brown Adipose Tissue Enhance Heart Function and MetabolismR01HL138738 · NHLBI · OHIO STATE UNIVERSITY · PI STANFORD, KRISTIN I · 2017 to 2021
$2.3MMuscle function and depression-like behavior in a mouse model of cancer fatigueR01NR012618 · NINR · OHIO STATE UNIVERSITY · PI REISER, PETER J, WOLD, LOREN EUGENE · 2012 to 2016
$2.2MDefining the Impact of E-Cigarettes on Cardiac PathophysiologyR01HL139348 · NHLBI · OHIO STATE UNIVERSITY · PI WOLD, LOREN EUGENE · 2017 to 2020
$1.9MSynergistic effects of obesity and air pollution on cardiac functionR01ES019923 · NIEHS · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI WOLD, LOREN EUGENE · 2011 to 2015
$1.8MPulmonary Vascular Dysfunction after Deployment-Related ExposuresI01CX001515 · VA · VA NEW JERSEY HEALTH CARE SYSTEM · PI FALVO, MICHAEL J. · 2018 to 2021
–CSRD VA I01 CX001329CSRD VA I01 CX001515NHLBI NIH HHS R01 HL138738NHLBI NIH HHS R01 HL139348NIA NIH HHS R01 AG057046NIEHS NIH HHS R01 ES019923NINR NIH HHS R01 NR012618
Abstract
Background Particulate matter (particles < 2.5 μm [ PM
Indexed as
AnimalsCalcium SignalingEpigenesis, GeneticFemaleGene Expression Regulation, DevelopmentalInflammation MediatorsInhalation ExposureMaleMaternal ExposureMiceMyocardial ContractionMyocytes, CardiacOxidative StressParticle SizeParticulate MatterPaternal ExposureInflammation MediatorsParticulate Mattercalciumcardiovascular functioninflammationmyocyteparticulate matterpreconception
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
NCT04974580ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.