Evidence map›Paper›PMID 30561064›Full record

ReviewThe British journal of dermatology2019

The diagnosis and classification of amyopathic dermatomyositis: a historical review and assessment of existing criteria.

J S S Concha, M Tarazi, C J Kushner, R G Gaffney, V P Werth

Open access · greenAbstract readHistorical ArticleReview
In one paragraph

Review in The British journal of dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J S S ConchaDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.ORCID 0000-0002-4421-1147
M TaraziDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.ORCID 0000-0001-7535-2914
C J KushnerDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.ORCID 0000-0002-7958-3186
R G GaffneyDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.ORCID 0000-0003-0272-446X
V P WerthDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.ORCID 0000-0003-3030-5369
Philadelphia VA Medical Center · US

Funding

Treatment of Dermatomyositis with Ajulemic Acid, a Non-Psychoactive CannabinoidR21AR066286 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI WERTH, VICTORIA P · 2014 to 2016
$387k
NIAMS NIH HHS R21 AR066286NIH HHS R21 AR066286
6 · The paper itself

Abstract

backgroundDiagnostic criteria are used to identify a patient having a disease in a clinical setting, whereas classification criteria create a well-defined population for research purposes. The diagnosis and classification of amyopathic dermatomyositis (ADM) have not been recognized by most existing criteria for idiopathic inflammatory myopathies (IIMs). To address this, several criteria were proposed to define ADM either as a distinct disease entity or as a subset of the spectrum of IIMs.

objectivesTo discuss the diagnosis and classification of ADM and to assesses the available criteria in identifying cases of ADM and/or distinguishing it from dermatological mimickers such as lupus erythematosus.

methodsWe conducted an extensive literature search using the PubMed database from June 2016 to August 2018, using the search terms 'amyopathic dermatomyositis', 'diagnosis' and 'classification'.

resultsThe European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) criteria, which are the only validated classification criteria for adult and juvenile IIM and their major subgroups, include three cutaneous items (Göttron sign, Göttron papules, heliotrope rash) to be able to classify ADM. This international and multispecialty effort is a huge step forward in the classification of skin-predominant disease in dermatomyositis. However, about 25% of the population with ADM do not meet two out of the three skin features and are misdiagnosed or classified as having a different disease entity, most commonly lupus erythematosus.

conclusionsThese gaps rationalize the continuous assessment and improvement of existing criteria and/or the development of validated, separate and skin-focused criteria for DM.

Indexed as

DermatologyDermatomyositisDiagnosis, DifferentialHistory, 20th CenturyHistory, 21st CenturyHumansLupus Erythematosus, CutaneousRheumatologySkin

Identifiers

PMID30561064
PMCPMC10226772
OpenAlexW2904259347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.