Evidence map›Paper›PMID 30560911›Full record

SynthesisEye (London, England)2019

Iatrogenic retinal breaks and postoperative retinal detachments in microincision vitrectomy surgery compared with conventional 20-gauge vitrectomy: a meta-analysis.

G H Chen, R Tzekov, F Z Jiang, S H Mao, Y H Tong, W S Li

Open access · bronzeAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Vitrectomy as a Prevention for Retinal Detachment in High-Risk Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Vitreous hemorrhage - Causes, diagnosis, and management.Indian journal of ophthalmology · 2023
    Review
  11. Article
  12. Article
  13. The risk of rhegmatogenous retinal detachment following anterior vitrectomy during cataract surgery: with versus without pars plana vitrectomy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

G H ChenDepartment of Ophthalmology, Quzhou People's Hospital, Quzhou, Zhejiang, People's Republic of China.
R TzekovDepartment of Ophthalmology, University of South Florida, Tampa, FL, USA.
F Z JiangDepartment of Ophthalmology, Quzhou People's Hospital, Quzhou, Zhejiang, People's Republic of China.
S H MaoDepartment of Ophthalmology, Quzhou People's Hospital, Quzhou, Zhejiang, People's Republic of China.
Y H TongDepartment of Ophthalmology, Quzhou People's Hospital, Quzhou, Zhejiang, People's Republic of China.
W S LiShanghai Aier Eye Hospital, 1286 Hongqiao Road, Shanghai, People's Republic of China. drlws@qq.com.
Quzhou City People's Hospital · CNShanghai Eye Disease Prevention & Treatment Center · CNUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the incidence of iatrogenic retinal breaks (IRBs) and postoperative retinal detachments (RDs) in microincision vitrectomy surgery (MIVS) compared with 20-gauge (20 G) vitrectomy.

methodsA comprehensive literature search was performed to find relevant studies and a meta-analysis of the IRBs and postoperative RDs rates after 20 G vitrectomy versus MIVS was conducted.

resultsThirty-two studies were selected, including 14,373 eyes (6932 eyes in the 20 G group, 7441 eyes in the MIVS group). The meta-analysis demonstrated that the incidence of IRBs was significantly higher in 20 G vitrectomy vs. MIVS (OR = 2.22, 95% CI, 1.93-2.57, P < 0.00001) and in a subanalysis vs. 23 G MIVS (OR = 2.19, 95% CI, 1.87-2.56, P < 0.00001) and vs. 25 G MIVS (OR = 2.27, 95% CI, 1.62-3.18, P < 0.00001). Similar result was obtained in a subanalysis for macular surgery (OR = 2.44, 95% CI, 1.99-2.99, P < 0.00001), and also for sclerotomy-related IRBs (OR = 3.73, 95% CI, 2.55-5.44, P < 0.00001), but not for surgically induced posterior vitreous detachment-related IRBs (OR = 1.59, 95% CI, 0.89-2.84, P = 0.12). The incidence of postoperative RDs in 20 G vitrectomy was significantly higher compared to MIVS (OR = 1.72, 95% CI, 1.21-2.46, P = 0.003) and in a subanalysis vs. 23 G MIVS (OR = 2.45, 95% CI, 1.50-4.00, P = 0.0003), but not for 25 G MIVS (OR = 1.01, 95% CI, 0.63-1.64, P = 0.96). Similar result was obtained in a subanalysis for macular surgery (OR = 1.89, 95% CI, 1.26-2.85, P = 0.002).

conclusionThis meta-analysis demonstrated that MIVS is associated with a lower risk of IRBs and postoperative RDs compared to 20 G vitrectomy.

Indexed as

Postoperative ComplicationsAgedFemaleHumansIatrogenic DiseaseIncidenceMaleMicrosurgeryMiddle AgedRetinal DetachmentRetinal PerforationsRetrospective StudiesVisual AcuityVitrectomyVitreous Body

Identifiers

PMID30560911
PMCPMC6707291
OpenAlexW2904932970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.