Evidence map›Paper›PMID 30560888›Full record

ArticleScientific reports2018

Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.

Cátia Fernandes-Cerqueira, Nuria Renard, Antonella Notarnicola, Edvard Wigren, Susanne Gräslund, Roman A Zubarev, Ingrid E Lundberg, Susanna L Lundström

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Cátia Fernandes-CerqueiraDivision of Rheumatology, Department of Medicine, Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Nuria RenardDivision of Rheumatology, Department of Medicine, Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Antonella NotarnicolaDivision of Rheumatology, Department of Medicine, Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Edvard WigrenDivision of Rheumatology, Department of Medicine, Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Susanne GräslundDivision of Rheumatology, Department of Medicine, Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Roman A ZubarevDivision of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solnavägen 9, SE- 171 77, Stockholm, Sweden.
Ingrid E LundbergDivision of Rheumatology, Department of Medicine, Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Susanna L LundströmDivision of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solnavägen 9, SE- 171 77, Stockholm, Sweden. susanna.lundstrom@ki.se.
Karolinska Institutet · SEKarolinska University Hospital · SEStructural Genomics Consortium · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgG Fc-glycans affect IgG function and are altered in autoimmune diseases and autoantibodies. Anti-histidyl tRNA synthetase autoantibodies (anti-Jo1) are frequent in patients with idiopathic inflammatory myopathies (IIM) and anti-synthetase syndrome (ASS) with associated interstitial lung disease (ILD). Thus, we hypothesized that the total-IgG Fc-glycans from Jo1

Indexed as

AdultAgedAutoantibodiesAutoantigensAutoimmune DiseasesAutoimmunityCase-Control StudiesFemaleGlycosylationHumansImmunoglobulin Fc FragmentsImmunoglobulin GMaleMiddle AgedPolysaccharidesAutoantibodiesAutoantigensImmunoglobulin Fc FragmentsImmunoglobulin GPolysaccharides

Identifiers

PMID30560888
PMCPMC6298993
OpenAlexW2904334266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.