ArticleeLife2018
Odor-evoked category reactivation in human ventromedial prefrontal cortex during sleep promotes memory consolidation.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Promoting memory consolidation during sleep: A meta-analysis of targeted memory reactivation.Psychological bulletin · 2020Pooled it
- Effects of Olfactory Learning Context Reactivation During Sleep on Training Success in a Double-Blind Randomized Controlled Sensorimotor Rhythm Neurofeedback Protocol: A Pilot Study.Psychophysiology · 2025Trial
- Odor-Cued Targeted Reactivation Was Unable to Selectively Benefit Declarative Memories During Sleep.Journal of sleep research · 2026Article
- An abstract relational map emerges in the human medial prefrontal cortex with consolidation.Current biology : CB · 2026Article
- Reactivation during sleep segregates the neural representations of episodic memories.bioRxiv : the preprint server for biology · 2026Article
- Memory reactivation during rest forms shortcuts in a cognitive map.Scientific reports · 2025Article
- The role of the parahippocampal cortex in memory consolidation for scenes.Learning & memory (Cold Spring Harbor, N.Y.) · 2025Article
- Characterizing Olfactory Brain Responses in Young Infants.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Electrophysiological signatures underlying variability in human memory consolidation.Nature communications · 2025Article
- Distributed and gradual microstructure changes are associated with the emergence of behavioural benefit from memory reactivation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Memory reactivation generates new, adaptive behaviours that reach beyond direct experience.Scientific reports · 2024Article
- Replay-triggered brain-wide activation in humans.Nature communications · 2024Article
- Modulating social learning-induced evaluation updating during human sleep.NPJ science of learning · 2024Article
- Effects of Targeted Memory Reactivation on Cortical Networks.Brain sciences · 2024Article
- Cueing memory reactivation during NREM sleep engenders long-term plasticity in both brain and behaviour.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neural reactivation during human sleep.Emerging topics in life sciences · 2023Review
- Item-specific neural representations during human sleep support long-term memory.PLoS biology · 2023Article
- Review
- Article
- Rule Abstraction Is Facilitated by Auditory Cuing in REM Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
Corrections and comments
- Commented on byLet's replay.2018
Authors and funding
5 authors.
Funding
Abstract
Slow-wave sleep is an optimal opportunity for memory consolidation: when encoding occurs in the presence of a sensory cue, delivery of that cue during sleep enhances retrieval of associated memories. Recent studies suggest that cues might promote consolidation by inducing neural reinstatement of cue-associated content during sleep, but direct evidence for such mechanisms is scant, and the relevant brain areas supporting these processes are poorly understood. Here, we address these gaps by combining a novel olfactory cueing paradigm with an object-location memory task and simultaneous EEG-fMRI recording in human subjects. Using pattern analysis of fMRI ensemble activity, we find that presentation of odor cues during sleep promotes reactivation of category-level information in ventromedial prefrontal cortex that significantly correlates with post-sleep memory performance. In identifying the potential mechanisms by which odor cues selectively modulate memory in the sleeping brain, these findings bring unique insights into elucidating how and what we remember.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.