Evidence map›Paper›PMID 30560501›Full record

ArticleLa Radiologia medica2019

Dynamic contrast-enhanced magnetic resonance imaging in locally advanced rectal cancer: role of perfusion parameters in the assessment of response to treatment.

Maria Ciolina, Damiano Caruso, Domenico De Santis, Marta Zerunian, Marco Rengo, Norma Alfieri, Daniela Musio, Francesca De Felice, Antonio Ciardi, Vincenzo Tombolini and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in La Radiologia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Delta radiomics: a systematic review.La Radiologia medica · 2021
    Pooled it
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  6. Correlation of KJournal for immunotherapy of cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Maria CiolinaDepartment of Surgical and Medical Sciences and Translational Medicine, "Sapienza" University of Rome, Radiology Unit - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
Damiano CarusoDepartment of Surgical and Medical Sciences and Translational Medicine, "Sapienza" University of Rome, Radiology Unit - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
Domenico De SantisDepartment of Surgical and Medical Sciences and Translational Medicine, "Sapienza" University of Rome, Radiology Unit - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
Marta ZerunianDepartment of Surgical and Medical Sciences and Translational Medicine, "Sapienza" University of Rome, Radiology Unit - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
Marco RengoDepartment of Surgical and Medical Sciences and Translational Medicine, "Sapienza" University of Rome, Radiology Unit - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
Norma AlfieriDepartment of Radiological Sciences, Oncology and Pathology, UOC Radiologia, Policlinico Umberto I Hospital, "Sapienza" University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy.
Daniela MusioDepartment of Radiological Sciences, Oncology and Pathology, UOC Radioterapia, Policlinico Umberto I Hospital, "Sapienza" University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy.
Francesca De FeliceDepartment of Radiological Sciences, Oncology and Pathology, UOC Radioterapia, Policlinico Umberto I Hospital, "Sapienza" University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy.
Antonio CiardiDepartment of Radiological Sciences, Oncology and Pathology, UOC Anatomia-Patologica, Policlinico Umberto I Hospital, "Sapienza" University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy.
Vincenzo TomboliniDepartment of Radiological Sciences, Oncology and Pathology, UOC Radioterapia, Policlinico Umberto I Hospital, "Sapienza" University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy.
Andrea LaghiDepartment of Surgical and Medical Sciences and Translational Medicine, "Sapienza" University of Rome, Radiology Unit - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy. andrea.laghi@uniroma1.it.ORCID http://orcid.org/0000-0002-3091-7819
Azienda Ospedaliera Sant'Andrea · ITPoliclinico Umberto I · IT

Funding

AIRC 2013/14129
6 · The paper itself

Abstract

purposeTo correlate dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters to tumor grading and to assess their reliability in predicting pathological complete response (pCR) before neoadjuvant chemoradiotherapy (CRT) in patients with locally advanced rectal cancer (LARC). MATERIALS AND

methodsForty patients (24 male; mean age, 67.3 ± 8.1 years) with histologically proven LARC who had undergone 3-Tesla DCE-MRI before (MRI_1) and after CRT (MRI_2) between August 2015 and February 2016 were included in this retrospective study. DCE-MRI parameters at MRI_1 and MRI_2 were extracted by two board certified radiologists in consensus reading with Olea Sphere 2.3 software using the extended Tofts model. Based on DCE-MRI results, patients were divided in complete responders (CR) and non-complete responders (nCR) and the perfusion parameters were correlated to tumor grading and pCR.

resultsWash-out and K

conclusionWash-out and K

Indexed as

AgedBiomarkersChemoradiotherapyContrast MediaFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMeglumineNeoplasm GradingNeoplasm StagingOrganometallic CompoundsPolymerase Chain ReactionRectal NeoplasmsRetrospective StudiesBiomarkersContrast Mediagadobenic acidMeglumineOrganometallic CompoundsImaging biomarkersLocally advanced rectal cancerMagnetic resonance imagingNeoadjuvant therapyPatient outcome

Identifiers

PMID30560501
OpenAlexW2904015851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.