ArticleJournal of neurology2019
Moyamoya angiopathy: long-term follow-up study in a Finnish population.
Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Clinical Efficacy of Revascularization Surgery for Moyamoya Angiopathy: Long-Term Results of a European Cohort.European journal of neurology · 2026Article
- Increased plasma fibronectin mirrors intimal phenotypic switching of vascular smooth muscle cells in moyamoya arteriopathy.Scientific reports · 2025Article
- Long-Term Outcome of Moyamoya Disease.Acta neurochirurgica. Supplement · 2025Article
- The pivotal role of neurosurgeons in transitional care: A comprehensive tertiary healthcare institution's experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- [Moyamoya in Aragon: epidemiology and self-perception of quality of life].Revista de neurologia · 2023Article
- Moyamoya Disease: Clinical and Radiological Characteristics in Adult Greek Patients.Journal of clinical medicine · 2023Article
- Progression of initially unilateral Moyamoya angiopathy in Caucasian Europeans.Journal of neurology · 2023Article
- The angiographic presentation of European Moyamoya angiopathy.Journal of neurology · 2022Observational
- Pediatric Moyamoya Disease and Syndrome in Italy: A Multicenter Cohort.Frontiers in pediatrics · 2022Article
- Progression in Moyamoya Disease: Clinical Features, Neuroimaging Evaluation, and Treatment.Current neuropharmacology · 2022Review
- Clinical Management of Moyamoya Patients.Journal of clinical medicine · 2021Review
- Neuropsychological impairment in adults with moyamoya angiopathy: preoperative assessment and correlation to MRI and HNeurosurgical review · 2020Article
- Moyamoya angiopathy: radiological follow-up findings in Finnish patients.Journal of neurology · 2020Article
- Histopathology of Moyamoya angiopathy in a European patient.Journal of neurology · 2019Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeMoyamoya angiopathy (MMA) is a chronic cerebrovascular disorder predominantly starting in childhood or early adulthood and thus affects the whole lifetime. Little is known on MMAs long-term outcomes in European patients. We report long-term follow-up data on Finnish MMA patients.
methodsWe included patients from our Helsinki University Hospital MMA database and arranged long-term follow-up visits for all the patients. This follow-up included a review of the medical records accumulated in due time, detailed neurological and neuropsychological evaluation, and outcome measures modified Rankin Scale (mRS) and Barthel Index (BI).
resultsThere were 61 MMA patients with a mean follow-up period of 9.5 years (SD 6.7 years; range 1.3-35.4 years; 581 patient-years). Only two patients had died and two-thirds (n = 40, 65.6%) had no new events during the follow-up period. Eight patients (13.1%) had an ischemic and five patients (8.2%) a hemorrhagic stroke during the follow-up. There were no differences between operated (n = 26) and conservatively (n = 35) treated groups regarding recurrent events or the outcome measured with mRS or BI. Finnish MMA patients reported significantly poorer physical and psychological health aspects of QOL when compared to the general Finnish population. Symptoms of low mood were found in 27 (56%) patients.
conclusionsFinnish MMA patients have a benign and stable course with a ~3.5 % annual stroke risk. We found no differences in the clinical outcomes between the operated and conservative groups, however, the psychosocial well-being requires more attention in MMA patients.
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