Evidence map›Paper›PMID 30560414›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019

Swept source optical coherence tomography analysis of choroidal thickness in macular telangiectasia type 2: a case-control study.

Vinod Kumar, Devesh Kumawat, Pradeep Kumar

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vinod KumarDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Devesh KumawatDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. deveshkumawat21@gmail.com.ORCID http://orcid.org/0000-0003-0204-7024
Pradeep KumarDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere has been a recent interest in the association of macular telangiectasia (MacTel) type 2 with central serous choroidopathy and other pachychoroid disorders. This study was performed to assess the subfoveal choroidal thickness (SFCT) in patients with MacTel type 2 and compare it with healthy controls using swept source optical coherence tomography (SS-OCT).

methodsIt was a retrospective case-control study performed at a tertiary eye care center. The cases constituted patients with MacTel type 2 detected over the last 2 years (April 2016 to March 2018). The controls were healthy adults with no posterior segment pathology. The patients were evaluated with color fundus photography, SS-OCT (Triton, Topcon Inc., Oakland, New Jersey, USA) and fundus fluorescein angiography. The cases were staged based on Gass and Blodi classification. SFCT was compared between the two groups.

resultsSixty-five eyes of 33 patients with MacTel were included. The controls consisted of 61 eyes of 33 healthy age-matched (p = 0.81) and sex-matched (p = 0.31) adults. The mean SFCT in cases (353.0 ± 91.2 μm) was higher than controls (289.2 ± 69.0 μm), and this difference was statistically significant (p = 0.0001). The mean SFCT was different in various stages: 346.6 ± 86.3 μm (stage 2), 334.6 ± 90.2 μm (stage 3), 374.6 ± 94.0 μm (stage 4), and 294.8 ± 68.8 μm (stage 5), though this was not statistically significant (p = 0.28).

conclusionsThe choroid in MacTel type 2 patients was significantly thickened as compared to controls. SFCT may vary as the structural changes worsen over time.

Indexed as

AdultAgedCase-Control StudiesChoroidFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansImage EnhancementMacula LuteaMaleMiddle AgedReproducibility of ResultsRetinal TelangiectasisRetrospective StudiesEnhanced depth imagingMacular telangiectasia type 2Subfoveal choroidal thicknessSwept source optical coherence tomography

Identifiers

PMID30560414
OpenAlexW2904856880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.