ArticleEuropean journal of nutrition2020
Effect of Vitamin A status during pregnancy on maternal anemia and newborn birth weight: results from a cohort study in the Western Brazilian Amazon.
Article in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Vitamin a supplementation during pregnancy in shaping child growth outcomes: A meta-analysis.Critical reviews in food science and nutrition · 2023Pooled it
- Vitamin A intake and status and associations with iron status, anaemia and birth outcomes of pregnant women in the Free State Province, South Africa: the Nutritional Status of Expectant Mothers and their newborn Infants (NuEMI) study.The British journal of nutrition · 2026Article
- Maternal vitamin A levels during second and third trimester and associations with offspring's birth weight: a longitudinal cohortFrontiers in nutrition · 2026Article
- The effect of multiple micronutrients supplementation on preventing anemia during pregnancy: a retrospective cohort study.Nutrition & metabolism · 2025Article
- Genetic predicted causal inferences between antioxidants and birth weight.Journal of clinical biochemistry and nutrition · 2024Article
- Plasma Retinol Concentrations and Dietary Intakes of Mother-Infant Sets in Singleton versus Twin Pregnancy.Nutrients · 2023Article
- The association between umbilical cord blood fat-soluble vitamin concentrations and infant birth weight.Frontiers in endocrinology · 2023Article
- Predictors of 25-hydroxyvitamin D concentrations during pregnancy: A longitudinal analysis in the Brazilian Amazon.European journal of clinical nutrition · 2022Article
- Geographic and socio-demographic determinants of plasma retinol concentrations in Chinese pregnant and lactating women.European journal of nutrition · 2022Article
- Common mental disorders in pregnancy and postnatal depressive symptoms in the MINA-Brazil study: occurrence and associated factors.Revista de saude publica · 2022Article
- Leisure-time physical activity in Amazonian pregnant women and offspring birth weight: A prospective cohort study.PloS one · 2022Article
- Associations between Maternal Dietary Patterns and Infant Birth Weight in the NISAMI Cohort: A Structural Equation Modeling Analysis.Nutrients · 2021Article
- Vitamin A Requirements in Pregnancy and Lactation.Current developments in nutrition · 2020Review
- [Relationship of plasma vitamin A levels between neonates and pregnant women in third trimester].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- Cohort profile: the Maternal and Child Health and Nutrition in Acre, Brazil, birth cohort study (MINA-Brazil).BMJ open · 2020Article
- Brazilian cohorts with potential for life-course studies: a scoping review.Revista de saude publica · 2020Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeInadequate Vitamin A (VA) status during pregnancy has been associated with maternal anemia and suboptimal newborn birth weight (BW). We assessed the effect of gestational serum retinol and β-carotene (µmol/L), in different moments during pregnancy, on maternal hemoglobin (Hb, g/L) and anemia (Hb < 110.0 g/L) at delivery, and newborn BW (kg).
methodsIn a prospective cohort study in Cruzeiro do Sul, Western Brazilian Amazon, biomarkers of the VA status were assessed in the second and third trimesters in pregnancy. Serum retinol and β-carotene were analyzed considering their effects in each and in both assessments (combined VA status), and the difference of serum values between assessments. Multiple linear and Poisson regression models were used with a hierarchical selection of covariates.
resultsA total of 488 mother-newborn pairs were surveyed. Combined VA deficiency status increased the risk for maternal anemia (adjusted prevalence ratio: 1.39; 95% CI 1.05-1.84), and was negatively associated with maternal Hb (β - 3.30 g/L; 95% CI - 6.4, - 0.20) and newborn BW (β - 0.10 kg; 95% CI - 0.20, - 0.00), adjusted for socioeconomic, environmental, obstetric, and antenatal characteristics, and nutritional indicators. However, the association for newborn BW was no longer significant after further adjustment for plasma ferritin. There were no significant associations between serum β-carotene and the outcomes studied.
conclusionPoor serum retinol status throughout pregnancy was associated with maternal anemia at delivery in Amazonian women. The current World Health Organization protocols for supplementation during antenatal care should consider VA status for planning recommendations in different scenarios.
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