ArticleLab on a chip2019
Acoustophoretic focusing effects on particle synthesis and clogging in microreactors.
Article in Lab on a chip, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Microfluidic Fabrication of Functional Micro-/Nanoparticles: From Structural Regulation to Scalable Integration.International journal of nanomedicine · 2026Review
- Ultrasound-assisted continuous aqueous synthesis of sulfonate, imidazolate, and carboxylate MOFs with high space time yield.Communications chemistry · 2025Article
- Ultrasound mechanisms and their effect on solid synthesis and processing: a review.Chemical Society reviews · 2025Review
- Exploring operational boundaries for acoustic concentration of cell suspensions.Applied microbiology and biotechnology · 2024Article
- Heterogeneous photochemical reaction enabled by an ultrasonic microreactor.Reaction chemistry & engineering · 2023Article
- Organic Sonochemistry: A Chemist's Timely Perspective on Mechanisms and Reactivity.The Journal of organic chemistry · 2021Article
- Acoustic resonance and atomization for gas-liquid systems in microreactors.Ultrasonics sonochemistry · 2021Article
- Continuous Ultrasonic Reactors: Design, Mechanism and Application.Materials (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The handling of solids in microreactors represents a challenging task. In this paper, we present an acoustophoretic microreactor developed to manage particles in flow and to control the material synthesis process. The reactor was designed as a layered resonator with an actuation frequency of 1.21 MHz, in which a standing acoustic wave is generated in both the depth and width direction of the microchannel. The acoustophoretic force exerted by the standing wave on the particles focuses them to the channel center. A parametric study of the effect of flow rate, particle size and ultrasound conditions on the focusing efficiency was performed. Furthermore, the reactive precipitation of calcium carbonate and barium sulfate was chosen as a model system for material synthesis. The acoustophoretic focusing effect avoids solid deposition on the channel walls and thereby minimizes reactor fouling and thus prevents clogging. Both the average particle size and the span of the particle size distribution of the synthesized particles are reduced by applying high-frequency ultrasound. The developed reactor has the potential to control a wide range of material synthesis processes.
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Registered trials
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